SCHEMBL469732

SCHEMBL469732

CCOC(=O)C(Br)C(C)=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.48
LMNA P02545 2/20 0.48
HSD17B10 Q99714 1/20 0.48
FAAH O00519 1/20 0.47
TRPA1 O75762 1/20 0.42
ALOX15 P16050 1/20 0.40
MGAM O43451 1/20 0.40
GAA P10253 1/20 0.40
SI P14410 1/20 0.40
MGAM2 Q2M2H8 1/20 0.40
SOAT1 P35610 1/20 0.40
MAPT P10636 1/20 0.38
GLO1 Q04760 1/20 0.37
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
CA12 O43570 2/20 0.35
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
CA9 Q16790 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11686314 0.91 FAAH (0.42) ALDH1A1LMNAHSD17B10FAAHTRPA1
SCHEMBL166529 0.87 ALDH1A1 (0.50) ALDH1A1LMNAHSD17B10TRPA1ALOX15
Propane SCHEMBL6048777 0.84 ALDH1A1 (0.48) ALDH1A1LMNAHSD17B10TRPA1ALOX15
Isobutane SCHEMBL6048714 0.82 ALDH1A1 (0.46) ALDH1A1LMNAHSD17B10FAAHTRPA1
Butane SCHEMBL6048693 0.82 ALDH1A1 (0.46) ALDH1A1LMNAHSD17B10FAAHTRPA1
SCHEMBL10883177 0.82 ALDH1A1 (0.46) ALDH1A1LMNAHSD17B10TRPA1ALOX15
SCHEMBL28043833 0.81 ALDH1A1 (0.44) ALDH1A1LMNAHSD17B10FAAHTRPA1
SCHEMBL3218141 0.80 ALDH1A1 (0.43) ALDH1A1LMNAHSD17B10TRPA1ALOX15
SCHEMBL844675 0.78 SOAT1 (0.44) ALDH1A1LMNAHSD17B10TRPA1ALOX15
SCHEMBL11412088 0.78 ALOX15 (0.50) ALDH1A1LMNAHSD17B10TRPA1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 164 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117466915-A Chromone-containing benzo [ d ] imidazo [2,1-b ] thiazole compound and preparation method and application thereof 江西科技师范大学 2024-01-30 CN claimed
CN-116370632-A Cold gel for preventing chapped skin by combining photodynamic therapy and preparation method thereof 杭州惠康医疗器械有限公司 2023-07-04 CN claimed
CN-115772137-A Preparation method of febuxostat 济宁晟泰药业有限公司 2023-03-10 CN claimed
CN-112374994-B Preparation method of pentafluoroaniline 衢州学院 2022-07-01 CN claimed
CN-111995584-B Preparation method of oxalagrill intermediate 常州工学院 2022-03-29 CN claimed
CN-112374994-A Preparation method of pentafluoroaniline 衢州学院 2021-02-19 CN claimed
CN-111995584-A Preparation method of oxalagrill intermediate 常州工学院 2020-11-27 CN claimed
CN-108169399-B Method for separating impurities in ethyl demethylaminothiazolyloximate crude product 山东金城医药化工有限公司 2020-10-09 CN claimed
CN-110790720-A New preparation method of febuxostat intermediate 内蒙古京东药业有限公司 2020-02-14 CN claimed
CN-102627596-B A kind of preparation method of Esomeprazole TIANJIN JINGYIN PHARMACEUTICAL BIOTECHNOLOGY DEVELOPMENT CO., LTD. (CN) 2016-01-27 CN claimed
CN-102336640-A Synthesis method of halogen acetone NANTONG BAOKAI CHEMICAL CO LTD 2012-02-01 CN claimed
US-20260071098-A1 ULTRAVIOLET-BLOCKING ADHESIVE COMPOSITION, METHOD FOR PREPARING ADHESIVE RESIN BY USING SAME, AND ADHESIVE FILM MANUFACTURED USING SAME SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) 2026-03-12 US disclosed
EP-4696755-A1 ULTRAVIOLET-BLOCKING ADHESIVE COMPOSITION, METHOD FOR PREPARING ADHESIVE RESIN BY USING SAME, AND ADHESIVE FILM MANUFACTURED USING SAME Seoul National University R&DB Foundation (KR) 2026-02-18 EP disclosed
WO-2025124415-A1 TETRACYCLIC DERIVATIVES AS K-Ras G12D INHIBITORS NIKANG THERAPEUTICS INC. (US) 2025-06-19 WO disclosed
WO-2025123318-A1 TETRACYCLIC DERIVATIVES AS K-Ras G12D INHIBITORS SHANGHAI BLUERAY BIOPHARMA CO., LTD. (CN) 2025-06-19 WO disclosed
EP-0005379-B1 PHOTOSENSITIVE COMPOSITIONS CONTAINING CARBONYLIC HALIDES AS ACTIVATORS Dynachem Corporation (US) 1981-12-23 EP disclosed
US-4051250-A OXAZOLE, THIAZOLE MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1977-09-27 US disclosed
US-4004026-A Dicarboxylic acids and derivatives in the treatment of pain and inflammation CIBA-GEIGY CORPORATION (US) 1977-01-18 US disclosed
US-3940434-A ANTIINFLAMMATORY, ANALGESIC CIBA-GEIGY CORPORATION (US) 1976-02-24 US disclosed
US-3933840-A ANTIPHLOGISTIC MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260071098-A1 ULTRAVIOLET-BLOCKING ADHESIVE COMPOSITION, METHOD FOR PREPARING ADHESIVE RESIN BY USING SAME, AND ADHESIVE FILM MANUFACTURED USING SAME CDH1, ITGAM, ICAM1 ALDH1A1 427/4885LMNA 561/4885HSD17B10 2175/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.