Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 11/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 10/20 | 0.57 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3053461 | 1.00 | MAPK1 (0.59) | MAPK1ALDH1A1HDAC3HDAC1NR1H4 | |
| SCHEMBL31661694 | 1.00 | MAPK1 (0.59) | MAPK1ALDH1A1HDAC3HDAC1NR1H4 | |
| SCHEMBL4955604 | 0.98 | MAPK1 (0.57) | MAPK1ALDH1A1HDAC3HDAC1NR1H4 | |
| SCHEMBL4953682 | 0.94 | MEN1 (0.57) | ALDH1A1NR1H4KDM4EHPGD | |
| SCHEMBL31267470 | 0.91 | ALDH1A1 (0.62) | MAPK1ALDH1A1HDAC3HDAC1KDM4E | |
| SCHEMBL3688021 | 0.91 | ALDH1A1 (0.62) | MAPK1ALDH1A1HDAC3HDAC1KDM4E | |
| Octanedioate SCHEMBL15255207 | 0.89 | ALDH1A1 (0.49) | MAPK1ALDH1A1HDAC3HDAC1KDM4E | |
| SCHEMBL4955428 | 0.87 | ALDH1A1 (0.59) | MAPK1ALDH1A1KDM4EHPGD | |
| SCHEMBL866062 | 0.85 | ALDH1A1 (0.64) | MAPK1ALDH1A1HDAC3HDAC1KDM4E | |
| SCHEMBL19077949 | 0.84 | MAPK1 (0.63) | MAPK1ALDH1A1NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107636007-A | Beta hairpin peptide mimics | 波利弗尔股份公司 | 2018-01-26 | — | — | CN | disclosed |
| CN-107001425-A | Beta hairpin peptide mimics | 波利弗尔股份公司 | 2017-08-01 | — | — | CN | disclosed |
| CN-107001426-A | Beta-hairpin peptidomimetics | 波利弗尔股份公司 | 2017-08-01 | — | — | CN | disclosed |
| CN-102844327-B | Template-fixed peptidomimetics with CXCR7 modulatory activity | 波利弗尔股份公司 | 2016-10-26 | — | — | CN | disclosed |
| CN-105849119-A | Beta-hairpin peptidomimetics | 波利弗尔股份公司 | 2016-08-10 | — | — | CN | disclosed |
| CN-105324390-A | Beta-hairpin peptidomimetics | POLYPHOR AG | 2016-02-10 | — | — | CN | disclosed |
| US-8969026-B2 | Polymeric reverse micelles as selective extraction agents and related methods of MALDI-MS analysis | UNIVERSITY OF MASSACHUSETTS (US) | 2015-03-03 | — | — | US | disclosed |
| US-8969026-B2 | Polymeric reverse micelles as selective extraction agents and related methods of MALDI-MS analysis | UNIVERSITY OF MASSACHUSETTS (US) | 2015-03-03 | — | — | US | disclosed |
| US-20120183983-A1 | Polymeric Reverse Micelles as Selective Extraction Agents and Related Methods of MALDI-MS Analysis | UNIVERSITY OF MASSACHUSETTS | 2012-07-19 | — | — | US | disclosed |
| US-20120183983-A1 | Polymeric Reverse Micelles as Selective Extraction Agents and Related Methods of MALDI-MS Analysis | UNIVERSITY OF MASSACHUSETTS | 2012-07-19 | — | — | US | disclosed |
| WO-2009023158-A2 | POLYMERIC REVERSE MICELLES AS SELECTIVE EXTRACTION AGENTS AND RELATED METHODS OF MALDI-MS ANALYSIS | UNIVERSITY OF MASSACHUSETTS (US) | 2009-02-19 | — | — | WO | disclosed |
| US-7462735-B2 | Amino acid diamides in non α position which are useful as adjuvants for administration of biological active agents | LABORATORIOS FARMACEUTICOS ROVI, S.A. (ES) | 2008-12-09 | — | — | US | disclosed |
| EP-1781807-B1 | FLUORESCENCE-BASED KINETIC DETERMINATION OF TRANSGLUTAMINASE ACTIVITY | N ZYME BIOTEC GMBH (DE) | 2008-12-03 | — | — | EP | disclosed |
| US-20070191302-A1 | AMINO ACID DIAMIDES IN NON ALPHA POSITION WHICH ARE USEFUL AS ADJUVANTS FOR ADMINISTRATION OF BIOLOGICAL ACTIVE AGENTS | LABORATORIOS FARMACEUTICOS ROVI S.A. (ES) | 2007-08-16 | — | — | US | disclosed |
| EP-1652836-B1 | AMINO ACID DIAMIDES IN NON ALPHA POSITION USEFUL AS ADJUVANTS FOR THE ADMINISTRATION OF ACTIVE BIOLOGICAL AGENTS | ROVI LAB FARMACEUT SA (ES) | 2007-07-18 | — | — | EP | disclosed |
| EP-1652836-A1 | AMINO ACID DIAMIDES IN NON ALPHA POSITION USEFUL AS ADJUVANTS FOR THE ADMINISTRATION OF ACTIVE BIOLOGICAL AGENTS | LABORATORIOS FARMACEUTICOS ROVI, S.A. (ES) | 2006-05-03 | — | — | EP | disclosed |
| EP-1626095-A1 | Fluorescence-based kinetic determination of transglutaminase activity | N-Zyme BioTec GmbH (DE) | 2006-02-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070191302-A1 | AMINO ACID DIAMIDES IN NON ALPHA POSITION WHICH ARE USEFUL AS ADJUVANTS FOR ADMINISTRATION OF BIOLOGICAL ACTIVE AGENTS | NOS1, NOS3, ARG1 | MAPK1 273/4885ALDH1A1 1095/4885HDAC3 4007/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.