Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | IAPP | P10997 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | CTSG | P08311 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26724889 | 0.83 | GABRA1 (0.50) | GABRA1GABRB2L3MBTL1ESR1POLB | |
| SCHEMBL22781148 | 0.82 | GABRA1 (0.62) | GABRA1GABRB2ESR1KCNH2ELANE | |
| SCHEMBL29150808 | 0.81 | GABRA1 (0.48) | GABRA1GABRB2L3MBTL1KCNH2IAPP | |
| SCHEMBL18238961 | 0.80 | GABRA1 (0.42) | GABRA1GABRB2L3MBTL1IAPPPOLB | |
| SCHEMBL28829955 | 0.79 | GABRA1 (0.54) | GABRA1GABRB2ESR1KCNH2POLB | |
| SCHEMBL7188564 | 0.77 | L3MBTL1 (0.43) | L3MBTL1ESR1IAPPPOLBMEN1 | |
| SCHEMBL2545614 | 0.76 | IAPP (0.50) | GABRA1GABRB2L3MBTL1IAPPPOLB | |
| SCHEMBL9102212 | 0.74 | P2RX7 (0.45) | L3MBTL1ESR1IAPPMEN1ALDH1A1 | |
| SCHEMBL19822954 | 0.74 | GABRA1 (0.38) | GABRA1GABRB2ESR1KCNH2MEN1 | |
| SCHEMBL258675 | 0.73 | GABRA1 (0.63) | GABRA1GABRB2POLBELANECTSG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1486489-B1 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | DOW AGROSCIENCES LLC (US) | 2016-04-27 | — | — | EP | disclosed |
| EP-1516874-B1 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | DOW AGROSCIENCES LLC (US) | 2015-08-19 | — | — | EP | disclosed |
| EP-1204643-B1 | FUNGICIDAL HETEROCYCLIC AROMATIC AMIDES AND THEIR COMPOSITIONS, METHODS OF USE AND PREPARATION | DOW AGROSCIENCES LLC (US) | 2008-06-04 | — | — | EP | disclosed |
| US-7034035-B2 | Fungicidal mono-, bi-, and tri-cycloheteroalkyl amides and their compositions, methods of use and preparation | DOW AGROSCIENCES LLC (US) | 2006-04-25 | — | — | US | disclosed |
| US-6927225-B2 | Fungicidal 2-pyridyl alkyl amides and their compositions, methods of use and preparation | DOW AGROSCIENCES LLC (US) | 2005-08-09 | — | — | US | disclosed |
| EP-1516875-A1 | FUNGICIDAL HETEROCYCLIC AROMATIC AMIDES AND THEIR COMPOSITIONS, METHODS OF USE AND PREPARATION | Dow AgroSciences LLC (US) | 2005-03-23 | — | — | EP | disclosed |
| EP-1516874-A1 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | Dow AgroSciences LLC (US) | 2005-03-23 | — | — | EP | disclosed |
| EP-1493733-A2 | Fungicidal heterocyclic aromatic amides, their compositions and methods of use | Dow AgroSciences LLC (US) | 2005-01-05 | — | — | EP | disclosed |
| EP-1486489-A2 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | Dow AgroSciences LLC (US) | 2004-12-15 | — | — | EP | disclosed |
| US-6706740-B2 | CONTROLLING, PREVENTION FUNGI INFECTIONS | DOW AGROSCIENCES LLC | 2004-03-16 | — | — | US | disclosed |
| US-20030022903-A1 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | RICKS MICHAEL J (US) | 2003-01-30 | — | — | US | disclosed |
| US-20030018012-A1 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | RICKS MICHAEL J (US) | 2003-01-23 | — | — | US | disclosed |
| US-20030018052-A1 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | RICKS MICHAEL J (US) | 2003-01-23 | — | — | US | disclosed |
| US-20020177578-A1 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | RICKS MICHAEL J (US) | 2002-11-28 | — | — | US | disclosed |
| EP-1234824-A1 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | Dow AgroSciences LLC (US) | 2002-08-28 | — | — | EP | disclosed |
| EP-1234825-A2 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | Dow AgroSciences LLC (US) | 2002-08-28 | — | — | EP | disclosed |
| EP-1234826-A2 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | Dow AgroSciences LLC (US) | 2002-08-28 | — | — | EP | disclosed |
| EP-1234823-A2 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | Dow AgroSciences LLC (US) | 2002-08-28 | — | — | EP | disclosed |
| EP-1234827-A2 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | Dow AgroSciences LLC (US) | 2002-08-28 | — | — | EP | disclosed |
| US-6355660-B1 | HETEROCYCLIC FUNGICIDES SUBSTITUTED WITH AMIDE GROUPS | DOW AGROSCIENCES LLC | 2002-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030018012-A1 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | CYP4X1, CYP1A1, NAT1 | GABRA1 837/4885GABRB2 2298/4885L3MBTL1 3933/4885 |
| US-20020177578-A1 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | CYP4X1, CYP1A1, NAT1 | GABRA1 837/4885GABRB2 2298/4885L3MBTL1 3933/4885 |
| US-20030022903-A1 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | CYP4X1, NAT1, CYP1A1 | GABRA1 1028/4885GABRB2 2426/4885L3MBTL1 4069/4885 |
| US-20030018052-A1 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | NAT1, CYP4X1, CYP1A1 | GABRA1 978/4885GABRB2 2437/4885L3MBTL1 3904/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.