Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 6/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.43 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.43 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.43 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.43 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.43 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4702930 | 0.93 | L3MBTL1 (0.44) | APPL3MBTL1ALDH1A1TSHRPSEN1 | |
| SCHEMBL4704779 | 0.91 | GPR119 (0.44) | APPL3MBTL1TSHRKMT2AGPR119 | |
| SCHEMBL4699744 | 0.91 | ALDH1A1 (0.47) | APPALDH1A1TSHRLMNAOPRD1 | |
| SCHEMBL4703685 | 0.89 | L3MBTL1 (0.54) | APPL3MBTL1ALDH1A1TSHRPSEN1 | |
| SCHEMBL4700627 | 0.82 | L3MBTL1 (0.53) | APPL3MBTL1ALDH1A1TSHRPSEN1 | |
| SCHEMBL4702948 | 0.81 | APP (0.57) | APPL3MBTL1ALDH1A1TSHRPSEN1 | |
| SCHEMBL6160222 | 0.81 | OPRM1 (0.53) | APPTSHRPSEN1PSEN2APH1B | |
| SCHEMBL4702942 | 0.81 | APP (0.44) | APPL3MBTL1ALDH1A1TSHRPSEN1 | |
| SCHEMBL9528495 | 0.80 | APP (0.66) | APPL3MBTL1ALDH1A1PSEN1PSEN2 | |
| SCHEMBL4789410 | 0.79 | HTR1A (0.42) | L3MBTL1TSHRMEN1KMT2AGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1635828-B1 | 4-(2-PHENYLOXYPHENYL)-PIPERIDINE OR -1,2,3,6-TETRAHYDROPYRIDINE DERIVATIVES AS SEROTONIN REUPTAKE INHIBITORS | LUNDBECK & CO AS H (DK) | 2008-04-23 | — | — | EP | disclosed |