Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.52 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5778800 | 0.98 | HRH3 (0.54) | HRH3HDAC3HDAC6CYP2A6CYP2A13 | |
| Benzene SCHEMBL28037716 | 0.94 | ALDH1A1 (0.56) | HRH3HDAC3HDAC6CYP2A6CYP2A13 | |
| Hydrochloric Acid SCHEMBL9442706 | 0.92 | HRH3 (0.65) | HRH3HDAC3HDAC6CYP2A6CYP2A13 | |
| SCHEMBL22614018 | 0.89 | HRH3 (0.45) | HRH3HDAC3HDAC6CYP2A6CYP2A13 | |
| SCHEMBL23902845 | 0.87 | HDAC3 (0.44) | HRH3HDAC3HDAC6CYP2A6CYP2A13 | |
| SCHEMBL13480470 | 0.83 | CYP2A6 (0.48) | HRH3HDAC3HDAC6CYP2A6CYP2A13 | |
| SCHEMBL23911919 | 0.83 | CYP2A6 (0.48) | HRH3HDAC3HDAC6CYP2A6CYP2A13 | |
| SCHEMBL6206033 | 0.82 | ALDH1A1 (0.46) | HRH3HDAC3HDAC6CYP2A6CYP2A13 | |
| SCHEMBL2043393 | 0.80 | HRH3 (0.61) | HRH3HDAC6CYP2A6CYP2A13ALDH1A1 | |
| SCHEMBL659509 | 0.80 | HRH3 (0.82) | HRH3HDAC3HDAC6ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118925523-A | Anti-biodegradation water-stable acetate fiber filtering membrane and preparation method thereof | 河南崇鑫净化材料有限公司 | 2024-11-12 | — | — | CN | claimed |
| US-6380197-B1 | FOR TREATING AND PREVENTING A PLETHORA OF DISEASES INCLUDING DIABETES | AVENTIS PHARMA S. A. (FR) | 2002-04-30 | — | — | US | claimed |
| JP-3099094-A | — | — | None | — | — | JP | disclosed |
| CN-118925523-A | Anti-biodegradation water-stable acetate fiber filtering membrane and preparation method thereof | 河南崇鑫净化材料有限公司 | 2024-11-12 | — | — | CN | disclosed |
| CN-118925523-A | Anti-biodegradation water-stable acetate fiber filtering membrane and preparation method thereof | 河南崇鑫净化材料有限公司 | 2024-11-12 | — | — | CN | disclosed |
| US-12012411-B2 | Viral replication inhibitors | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2024-06-18 | — | — | US | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11364241-B2 | Dihydropyridophthalazinone inhibitors of poly(ADP-ribose)polymerase (PARP) | MEDIVATION TECHNOLOGIES LLC (US) | 2022-06-21 | — | — | US | disclosed |
| US-20220106321-A1 | VIRAL REPLICATION INHIBITORS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2022-04-07 | — | — | US | disclosed |
| US-11279704-B2 | Viral replication inhibitors | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2022-03-22 | — | — | US | disclosed |
| US-11168084-B2 | Purine based compounds as toll-like receptor 9 antagonist | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2021-11-09 | — | — | US | disclosed |
| US-20030004148-A1 | Regulation of meiosis | NOVO NORDISK A/S (DK) | 2003-01-02 | — | — | US | disclosed |
| US-6380197-B1 | FOR TREATING AND PREVENTING A PLETHORA OF DISEASES INCLUDING DIABETES | AVENTIS PHARMA S. A. (FR) | 2002-04-30 | — | — | US | disclosed |
| EP-1001943-A1 | POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | Aventis Pharma S.A. (FR) | 2000-05-24 | — | — | EP | disclosed |
| WO-1999003843-A1 | POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | RHONE-POULENC RORER S.A. (FR) | 1999-01-28 | — | — | WO | disclosed |
| JP-H0399094-A | LIQUID CRYSTAL-NATURED ESTER FROM ORGANIC ACID AND TRITERPENE ALCOHOL | SHIRATORI SEIYAKU KK | 1991-04-24 | — | — | JP | disclosed |
| US-4762845-A | BACTERICIDES | ABBOTT LABORATORIES (US) | 1988-08-09 | — | — | US | disclosed |
| EP-0039989-B1 | PYRIMIDONE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1984-08-29 | — | — | EP | disclosed |
| US-4388317-A | ANTIHISTAMINES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1983-06-14 | — | — | US | disclosed |
| EP-0039989-A1 | Pyrimidone derivatives, processes for their preparation and pharmaceutical compositions containing them | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1981-11-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11168084-B2 | Purine based compounds as toll-like receptor 9 antagonist | TLR9, TLR1, TLR7 | HRH3 200/4885HDAC3 3664/4885HDAC6 4130/4885 |
| US-11364241-B2 | Dihydropyridophthalazinone inhibitors of poly(ADP-ribose)polymerase (PARP) | PARP1, PARP2, PARP11 | HRH3 1620/4885HDAC3 99/4885HDAC6 132/4885 |
| US-20030004148-A1 | Regulation of meiosis | ALPG, MNS1, BUB1B | HRH3 3595/4885HDAC3 1300/4885HDAC6 1372/4885 |
| US-11279704-B2 | Viral replication inhibitors | EIF2AK2, MAVS, ZC3HAV1 | HRH3 1264/4885HDAC3 1559/4885HDAC6 1030/4885 |
| US-20220106321-A1 | VIRAL REPLICATION INHIBITORS | EIF2AK2, MAVS, ZC3HAV1 | HRH3 1264/4885HDAC3 1559/4885HDAC6 1030/4885 |
| US-12012411-B2 | Viral replication inhibitors | EIF2AK2, MAVS, ZC3HAV1 | HRH3 1264/4885HDAC3 1559/4885HDAC6 1030/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.