Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 5/20 | 0.44 |
| ▸ | ALDH3A1 | P30838 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12271942 | 0.89 | ALDH1A1 (0.51) | FABP4HTTALDH3A1L3MBTL1POLB | |
| SCHEMBL15074499 | 0.82 | HTT (0.66) | FABP4HTTALDH3A1L3MBTL1POLB | |
| SCHEMBL19911406 | 0.74 | ALOX5 (0.60) | HTTALDH3A1L3MBTL1POLBNOD1 | |
| SCHEMBL12576406 | 0.70 | HDAC8 (0.41) | HTTL3MBTL1LMNAALDH1A1KMT2A | |
| SCHEMBL14601697 | 0.69 | ALDH3A1 (0.68) | HTTALDH3A1L3MBTL1POLBNOD1 | |
| SCHEMBL19911391 | 0.68 | MET (0.53) | HTTALDH3A1L3MBTL1POLBNOD1 | |
| SCHEMBL19911385 | 0.67 | ALDH1A1 (0.67) | HTTALDH3A1L3MBTL1POLBNOD1 | |
| SCHEMBL19848546 | 0.66 | ALDH3A1 (0.71) | HTTALDH3A1L3MBTL1POLBNOD1 | |
| SCHEMBL6169770 | 0.66 | SMN1; SMN2 (0.74) | HTTALDH3A1L3MBTL1POLBNOD1 | |
| SCHEMBL6170599 | 0.66 | HTT (0.61) | HTTALDH3A1L3MBTL1POLBNOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012032065-A1 | INDAZOLE DERIVATIVES FOR USE IN THE TREATMENT OF INFLUENZA VIRUS INFECTION | GLAXO GROUP LIMITED (GB) | 2012-03-15 | — | — | WO | disclosed |
| WO-2011067364-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2011-06-09 | — | — | WO | disclosed |