Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 5/20 | 0.66 |
| ▸ | ALDH3A1 | P30838 | 4/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.66 |
| ▸ | FABP4 | P15090 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 5/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12271942 | 0.83 | ALDH1A1 (0.51) | HTTALDH3A1POLBNOD1L3MBTL1 | |
| SCHEMBL470318 | 0.82 | FABP4 (0.50) | HTTALDH3A1POLBNOD1L3MBTL1 | |
| SCHEMBL6170599 | 0.80 | HTT (0.61) | HTTALDH3A1POLBNOD1L3MBTL1 | |
| SCHEMBL19911331 | 0.80 | HTT (0.69) | HTTALDH3A1POLBNOD1L3MBTL1 | |
| SCHEMBL8329551 | 0.80 | ALDH3A1 (1.00) | HTTALDH3A1POLBNOD1L3MBTL1 | |
| SCHEMBL15410031 | 0.80 | L3MBTL1 (0.50) | HTTALDH3A1POLBNOD1L3MBTL1 | |
| SCHEMBL29408218 | 0.74 | MEN1 (0.60) | HTTL3MBTL1FABP4LMNATSHR | |
| SCHEMBL2573218 | 0.74 | MEN1 (0.60) | HTTL3MBTL1FABP4LMNATSHR | |
| SCHEMBL22128244 | 0.74 | KDM4E (0.45) | HTTALDH3A1POLBNOD1L3MBTL1 | |
| SCHEMBL31315856 | 0.74 | KDM4E (0.45) | HTTALDH3A1POLBNOD1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130165433-A1 | Novel Use | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2013-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130165433-A1 | Novel Use | HAVCR2, MAVS, ENTPD5 | HTT 3804/4885ALDH3A1 1903/4885POLB 1728/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.