Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.39 |
| ▸ | GLP1R | P43220 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5782346 | 0.89 | THRB (0.47) | THRBHPGDPTGER4HSD17B10KMT2A | |
| SCHEMBL5778385 | 0.87 | THRB (0.46) | THRBHPGDPTGER4HSD17B10KMT2A | |
| SCHEMBL4703386 | 0.87 | MCHR1 (0.47) | THRBHPGDPTGER4HSD17B10HCAR3 | |
| SCHEMBL4703169 | 0.87 | THRB (0.46) | THRBHPGDPTGER4HSD17B10KMT2A | |
| SCHEMBL4703384 | 0.85 | THRB (0.46) | THRBHPGDPTGER4HSD17B10HCAR3 | |
| SCHEMBL5815980 | 0.81 | LMNA (0.45) | THRBHPGDPTGER4HSD17B10HCAR3 | |
| SCHEMBL4702409 | 0.80 | THRB (0.44) | THRBHPGDPTGER4HSD17B10KMT2A | |
| SCHEMBL4703393 | 0.80 | THRB (0.46) | THRBHPGDPTGER4HSD17B10KMT2A | |
| SCHEMBL4703128 | 0.78 | FGFR1 (0.54) | THRBHPGDTP53 | |
| SCHEMBL4700682 | 0.78 | THRB (0.45) | THRBHPGDHSD17B10TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1615896-B1 | NOVEL BENZIMIDAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THESE COMPOUNDS | NEUROSEARCH AS (DK) | 2008-04-23 | — | — | EP | claimed |