Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | HRH2 | P25021 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5782346 | 0.91 | THRB (0.47) | LMNAL3MBTL1THRBHCAR3HPGD | |
| SCHEMBL5812811 | 0.87 | THRB (0.46) | LMNAL3MBTL1THRBHCAR3HPGD | |
| SCHEMBL4703386 | 0.84 | MCHR1 (0.47) | THRBHCAR3HPGDMCHR1HSD17B10 | |
| SCHEMBL5778385 | 0.83 | THRB (0.46) | THRBHPGDMCHR1HSD17B10PTGER4 | |
| SCHEMBL4703387 | 0.81 | THRB (0.44) | THRBHCAR3HPGDMCHR1HSD17B10 | |
| SCHEMBL4702408 | 0.78 | THRB (0.44) | THRBHCAR3HPGDHSD17B10PTGER4 | |
| SCHEMBL5782343 | 0.78 | THRB (0.48) | L3MBTL1THRBHCAR3HPGDMCHR1 | |
| SCHEMBL5777980 | 0.78 | THRB (0.49) | LMNAL3MBTL1THRBHCAR3HPGD | |
| SCHEMBL4698566 | 0.75 | HCAR3 (0.42) | LMNAL3MBTL1THRBHCAR3HPGD | |
| SCHEMBL5782481 | 0.74 | HSD17B10 (0.47) | LMNAL3MBTL1THRBHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1194410-B1 | BENZIMIDAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THESE COMPOUNDS | NEUROSEARCH AS (DK) | 2006-01-18 | — | — | EP | disclosed |