Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GLP1R | P43220 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | LIPE | Q05469 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5782346 | 0.91 | THRB (0.47) | THRBMCHR1HPGDPTGER4HSD17B10 | |
| SCHEMBL4703386 | 0.90 | MCHR1 (0.47) | THRBMCHR1HPGDPTGER4HSD17B10 | |
| SCHEMBL4703387 | 0.87 | THRB (0.44) | THRBMCHR1HPGDPTGER4HSD17B10 | |
| SCHEMBL5781887 | 0.87 | THRB (0.48) | THRBHPGDPTGER4HSD17B10KMT2A | |
| SCHEMBL5815980 | 0.83 | LMNA (0.45) | THRBMCHR1HPGDPTGER4HSD17B10 | |
| SCHEMBL5778383 | 0.82 | THRB (0.46) | THRBHPGDMGLLHSD17B10HTR1A | |
| SCHEMBL5777980 | 0.79 | THRB (0.49) | THRBHPGDPTGER4HSD17B10KMT2A | |
| SCHEMBL5782596 | 0.79 | THRB (0.48) | THRBHPGDPTGER4HSD17B10KMT2A | |
| SCHEMBL4703168 | 0.78 | THRB (0.48) | THRBHPGDPTGER4HSD17B10KMT2A | |
| SCHEMBL5781185 | 0.78 | THRB (0.48) | THRBHPGDPTGER4HSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1194410-B1 | BENZIMIDAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THESE COMPOUNDS | NEUROSEARCH AS (DK) | 2006-01-18 | — | — | EP | claimed |