Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 6/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 6/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4704854 | 1.00 | ESR1 (0.56) | ESR1MAPTALDH1A1HPGDKEAP1 | |
| SCHEMBL4699717 | 0.92 | ALDH1A1 (0.50) | ESR1MAPTALDH1A1HPGDKEAP1 | |
| SCHEMBL4699713 | 0.92 | ALDH1A1 (0.50) | ESR1MAPTALDH1A1HPGDKEAP1 | |
| SCHEMBL4702684 | 0.90 | BMP1 (0.48) | ESR1MAPTALDH1A1HPGDKEAP1 | |
| SCHEMBL4702685 | 0.90 | BMP1 (0.48) | ESR1MAPTALDH1A1HPGDKEAP1 | |
| SCHEMBL7364803 | 0.88 | ALDH1A1 (0.47) | ESR1MAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL7364808 | 0.88 | ALDH1A1 (0.47) | ESR1MAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL1884748 | 0.88 | ALDH1A1 (0.53) | ESR1MAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL1884750 | 0.88 | ALDH1A1 (0.53) | ESR1MAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL5531936 | 0.87 | MAPT (0.56) | MAPTALDH1A1HPGDKEAP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1648896-B1 | 7-SUBSTITUTED 3-NITRO-PYRAZOLO [1,5-A] PYRIMIDINES | FERRER INT (ES) | 2008-02-13 | — | — | EP | disclosed |
| US-20070043064-A1 | 7-Substituted 3-nitro-pyrazo[1,5-a] pyrimidines | FERRER INTERNACIONAL S.A. (ES) | 2007-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043064-A1 | 7-Substituted 3-nitro-pyrazo[1,5-a] pyrimidines | GABRB1, GABRA1, GABRB2 | ESR1 862/4885MAPT 2772/4885ALDH1A1 113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.