Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.82 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.82 |
| ▸ | LMNA | P02545 | 1/20 | 0.82 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.82 |
| ▸ | PKM | P14618 | 1/20 | 0.82 |
| ▸ | TSHR | P16473 | 1/20 | 0.82 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.82 |
| ▸ | BLM | P54132 | 1/20 | 0.82 |
| ▸ | AANAT | Q16613 | 1/20 | 0.70 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.67 |
| ▸ | MMP9 | P14780 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.60 |
| ▸ | GALR3 | O60755 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nb-Acetyltryptamine SCHEMBL468850 | 0.90 | MEN1 (1.00) | MEN1KMT2ALMNACYP1A2PKM | |
| Nb-Acetyltryptamine SCHEMBL29669230 | 0.89 | MEN1 (0.97) | MEN1KMT2ALMNACYP1A2PKM | |
| SCHEMBL761155 | 0.85 | MTNR1A (0.76) | MEN1KMT2ALMNACYP1A2PKM | |
| SCHEMBL31114206 | 0.85 | MTNR1A (0.76) | MEN1KMT2ALMNACYP1A2PKM | |
| SCHEMBL12762819 | 0.84 | MEN1 (0.76) | MEN1KMT2ALMNACYP1A2PKM | |
| Hydrochloric Acid SCHEMBL3826492 | 0.84 | MTNR1A (0.74) | MEN1KMT2ALMNACYP1A2PKM | |
| SCHEMBL761481 | 0.84 | MTNR1A (0.88) | MEN1KMT2ALMNACYP1A2PKM | |
| SCHEMBL7677886 | 0.83 | MEN1 (0.84) | MEN1KMT2ALMNACYP1A2PKM | |
| SCHEMBL5903804 | 0.83 | AANAT (0.77) | MEN1KMT2ALMNACYP1A2PKM | |
| SCHEMBL10069200 | 0.83 | AANAT (0.77) | MEN1KMT2ALMNACYP1A2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1390367-B1 | DIHYDROIMIDAZO 5,1-A -$G(b)-CARBOLINE DERIVATIVES, METHOD FOR PREPARING SAME AND USE THEREOF AS MEDICINE | MACEF (FR) | 2008-07-09 | — | — | EP | disclosed |
| US-7291627-B2 | Dihydroimidazo[5.1-a]-beta-carboline derivatives, method for their preparation, and their application as a drug | MACEF (FR) | 2007-11-06 | — | — | US | disclosed |
| WO-2007101863-A1 | THERAPEUTIC COMBINATION OF A 5HT2 RECEPTOR ANTAGONIST AND OF A 5HT2 RECEPTOR ACTIVATOR | MACEF (FR) | 2007-09-13 | — | — | WO | disclosed |
| US-20060089372-A1 | Dihydroimidazo[5,1-a]sg(b)-carboline derivatives, method for preparing same and use thereof as medicine | MACEF (FR) | 2006-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060089372-A1 | Dihydroimidazo[5,1-a]sg(b)-carboline derivatives, method for preparing same and use thereof as medicine | GDI2, GDI1, CYP2A7 | MEN1 2370/4885KMT2A 789/4885LMNA 3198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.