Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORB | Q92753 | 10/20 | 0.41 |
| ▸ | RORC | P51449 | 6/20 | 0.37 |
| ▸ | IDH1 | O75874 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.36 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4708752 | 0.94 | RORB (0.43) | RORBRORCIDH1P2RX7RPS6KA3 | |
| SCHEMBL4708283 | 0.92 | RORB (0.39) | RORBRORCIDH1P2RX7GRM2 | |
| SCHEMBL4706699 | 0.92 | RORB (0.42) | RORBRORCIDH1P2RX7GRM2 | |
| SCHEMBL4705879 | 0.87 | RORB (0.42) | RORBRORCIDH1GRM2 | |
| SCHEMBL4705482 | 0.87 | RORB (0.41) | RORBRORCIDH1GRM2TRPV1 | |
| SCHEMBL4708122 | 0.86 | RORB (0.39) | RORBRORCIDH1GRM2NTRK1 | |
| SCHEMBL4707066 | 0.86 | RORB (0.41) | RORBRORCIDH1P2RX7GRM2 | |
| SCHEMBL4708216 | 0.86 | IDH1 (0.42) | RORBRORCIDH1P2RX7NTRK1 | |
| SCHEMBL4709738 | 0.85 | RORB (0.42) | RORBRORCP2RX7RPS6KA3 | |
| SCHEMBL4708689 | 0.84 | RORB (0.40) | RORBRORCIDH1GRM2TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501809-B1 | TRIAZOLE DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 2008-01-16 | — | — | EP | disclosed |