Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | EED | O75530 | 1/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL470753 | 0.80 | KDM1A (0.55) | FUCA1DRD2DRD3S1PR1KDM1A | |
| SCHEMBL463076 | 0.79 | KMT2A (0.47) | SIGMAR1CYP3A4CYP2C9DRD2DRD3 | |
| SCHEMBL463075 | 0.79 | KMT2A (0.47) | SIGMAR1CYP3A4CYP2C9DRD2DRD3 | |
| SCHEMBL470646 | 0.75 | DRD2 (0.45) | SIGMAR1FUCA1DRD2DRD3S1PR1 | |
| SCHEMBL470519 | 0.73 | DPP4 (0.48) | SIGMAR1FUCA1DRD2DRD3KDM1A | |
| SCHEMBL7216583 | 0.72 | USP30 (0.53) | SIGMAR1S1PR1S1PR5 | |
| SCHEMBL7216590 | 0.72 | USP30 (0.53) | SIGMAR1S1PR1S1PR5 | |
| SCHEMBL7216580 | 0.72 | USP30 (0.53) | SIGMAR1S1PR1S1PR5 | |
| SCHEMBL6422642 | 0.72 | UBE2M (0.47) | SIGMAR1CYP3A4CYP2C9FUCA1NPY5R | |
| SCHEMBL13186825 | 0.71 | DRD2 (0.53) | SIGMAR1FUCA1DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |