Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 5/20 | 0.55 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.50 |
| ▸ | CCR5 | P51681 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | RORC | P51449 | 3/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | GBA1 | P04062 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19270973 | 0.85 | KDM1A (0.53) | KDM1AFUCA1CCR5MAOBMAOA | |
| SCHEMBL19270969 | 0.85 | KDM1A (0.53) | KDM1AFUCA1CCR5MAOBMAOA | |
| SCHEMBL1202493 | 0.84 | KDM1A (0.55) | KDM1AFUCA1CCR5MAOBMAOA | |
| SCHEMBL13229948 | 0.84 | KDM1A (0.55) | KDM1AFUCA1CCR5MAOBMAOA | |
| SCHEMBL2417901 | 0.84 | KDM1A (0.55) | KDM1AFUCA1CCR5MAOBMAOA | |
| SCHEMBL6571278 | 0.83 | CCR5 (0.60) | KDM1AFUCA1CCR5MAOBRORC | |
| SCHEMBL470646 | 0.81 | DRD2 (0.45) | KDM1AFUCA1MAOBMAOAS1PR1 | |
| SCHEMBL470591 | 0.80 | SIGMAR1 (0.44) | KDM1AFUCA1S1PR1S1PR5DRD2 | |
| SCHEMBL6624318 | 0.80 | FUCA1 (0.71) | KDM1AFUCA1CCR5RORCS1PR1 | |
| SCHEMBL470519 | 0.79 | DPP4 (0.48) | KDM1AFUCA1CCR5DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |