Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 8/20 | 0.43 |
| ▸ | CAMK1D | Q8IU85 | 9/20 | 0.38 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RIPK4 | P57078 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | MAP2K5 | Q13163 | 1/20 | 0.38 |
| ▸ | CAMK1 | Q14012 | 1/20 | 0.38 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.38 |
| ▸ | PNCK | Q6P2M8 | 1/20 | 0.38 |
| ▸ | CAMK1G | Q96NX5 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL470588 | 0.89 | GPR119 (0.46) | ACACB | |
| SCHEMBL470687 | 0.81 | GPR119 (0.39) | ACACBCAMK1DPIP5K1CCYP2C9CYP2C19 | |
| SCHEMBL470661 | 0.76 | GPR119 (0.47) | ACACBCAMK1DPIP5K1CCYP2C9CYP2C19 | |
| SCHEMBL470585 | 0.75 | GPR119 (0.35) | ACACBCAMK1DPIP5K1CCYP2C9CYP2C19 | |
| SCHEMBL13186861 | 0.75 | GPR119 (0.48) | ACACB | |
| SCHEMBL470599 | 0.70 | GPR119 (0.43) | ACACBCYP2C9 | |
| SCHEMBL12193392 | 0.69 | ACACB (0.47) | ACACB | |
| SCHEMBL470849 | 0.69 | GPR119 (0.41) | ACACBKCNH2HCRTR1HCRTR2 | |
| SCHEMBL2413103 | 0.69 | POLB (0.54) | CAMK1DPIP5K1CCYP2C9CYP2C19RIPK4 | |
| SCHEMBL26684586 | 0.67 | HRH3 (0.44) | ACACBCAMK1DPIP5K1CCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |