Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | CCR4 | P51679 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16795 | 0.81 | — | — | |
| SCHEMBL5559191 | 0.79 | ALDH1A1 (0.42) | EDNRAL3MBTL1CES2CES1HSD11B1 | |
| SCHEMBL3272540 | 0.75 | HTR6 (0.39) | EDNRAL3MBTL1CES2CES1HSD11B1 | |
| SCHEMBL3437251 | 0.71 | — | — | |
| SCHEMBL1035591 | 0.71 | — | — | |
| SCHEMBL354012 | 0.71 | — | — | |
| SCHEMBL6217014 | 0.71 | — | — | |
| SCHEMBL11387848 | 0.71 | L3MBTL1 (0.36) | EDNRAL3MBTL1CES2CES1HSD11B1 | |
| SCHEMBL1322510 | 0.71 | — | — | |
| SCHEMBL13290790 | 0.71 | CCR4 (0.39) | EDNRAL3MBTL1CES2CES1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1443822-B1 | SUBSTITUTED THIEN-3-YL-SULFONYLAMINO(THIO)CARBONYL-TRIAZOLIN(THI)ONES | BAYER CROPSCIENCE AG (DE) | 2008-12-17 | — | — | EP | disclosed |
| EP-1443822-A1 | SUBSTITUTED THIEN-3-YL-SULFONYLAMINO(THIO)CARBONYL-TRIAZOLIN(THI)ONES | Bayer CropScience AG (DE) | 2004-08-11 | — | — | EP | disclosed |
| WO-2003037086-A1 | SUBSTITUTED THIEN-3-YL-SULFONYLAMINO(THIO)CARBONYL-TRIAZOLIN(THI)ONES | BAYER CROPSCIENCE AG (DE) | 2003-05-08 | — | — | WO | disclosed |