⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3272540 | 0.79 | HTR6 (0.39) | — | |
| Ethylene SCHEMBL27589672 | 0.76 | TSHR (0.41) | — | |
| SCHEMBL1035591 | 0.75 | — | — | |
| SCHEMBL11387848 | 0.75 | L3MBTL1 (0.36) | — | |
| SCHEMBL354012 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL27394711 | 0.73 | TSHR (0.42) | — | |
| SCHEMBL27742303 | 0.73 | CA2 (0.42) | — | |
| SCHEMBL5559191 | 0.73 | ALDH1A1 (0.42) | — | |
| Lithium Ion SCHEMBL22394574 | 0.73 | LMNA (0.35) | — | |
| SCHEMBL9424788 | 0.73 | LMNA (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1575947-A1 | 2-OXOPYRIDIN-3-YL THIA(DI)AZOLE DERIVATIVES FOR USE IN THE TREATMENT OF CELL PROLIFERATION AND APOPTOSIS RELATED DISEASES | Amgen Inc. (US) | 2005-09-21 | — | — | EP | claimed |
| US-20040147561-A1 | Pyrid-2-one derivatives and methods of use | SYNGENTA CROP PROTECTION AG (CH) | 2004-07-29 | — | — | US | claimed |
| WO-2004060890-A1 | 2-OXOPYRIDIN-3-YL THIA (DI) AZOLE DERIVATES FOR USE IN THE TREATMENT OF CELL PROLIFERATION AND APOPTOSIS RELATED DISEASES | AMGEN INC. (US) | 2004-07-22 | — | — | WO | claimed |