Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | CCR2 | P41597 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9666902 | 0.79 | CCR2 (0.61) | CNR2CCR2L3MBTL1ALDH1A1KMT2A | |
| SCHEMBL2400013 | 0.78 | CCR2 (0.63) | CNR2CCR2L3MBTL1CYP1A2ALDH1A1 | |
| SCHEMBL9240559 | 0.75 | ALDH1A1 (0.64) | CCR2L3MBTL1CYP1A2ALDH1A1KMT2A | |
| SCHEMBL24170706 | 0.74 | CCR2 (0.47) | CNR2CCR2L3MBTL1CYP1A2ALDH1A1 | |
| SCHEMBL7837255 | 0.73 | MTNR1A (0.58) | CNR2CCR2CYP1A2ALDH1A1KMT2A | |
| SCHEMBL4198025 | 0.72 | MCL1 (0.57) | ALDH1A1KMT2AMEN1KDM4ENPC1 | |
| SCHEMBL9239991 | 0.72 | CCR2 (0.67) | CCR2MAPTSMN1; SMN2 | |
| SCHEMBL1392918 | 0.71 | NOD2 (0.64) | ALDH1A1KMT2AMEN1KDM4ERXFP1 | |
| SCHEMBL30585515 | 0.71 | NOD2 (0.64) | ALDH1A1KMT2AMEN1KDM4ERXFP1 | |
| SCHEMBL10289428 | 0.71 | CYP1A2 (0.49) | CNR2CCR2L3MBTL1CYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1625129-B1 | HETEROCYCLYL-SUBSTITUTED DIHYDROQUINAZOLINES AND USE THEREOF AS AN ANTIVIRAL AGENT | BAYER HEALTHCARE AG (DE) | 2008-03-05 | — | — | EP | disclosed |