SCHEMBL470760

SCHEMBL470760

N#C/C(=C1/c2ccccc2-c2c1c1c(c3c2/C(=C(\C#N)c2ccc4ccccc4c2)c2ccccc2-3)/C(=C(\C#N)c2ccc3ccccc3c2)c2ccccc2-1)c1ccc2ccccc2c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
F2 P00734 1/20 0.39
PLG P00747 1/20 0.39
PLAU P00749 1/20 0.39
KLKB1 P03952 1/20 0.39
KLK1 P06870 1/20 0.39
PRSS1 P07477 1/20 0.39
RAPGEF3 O95398 2/20 0.38
RAPGEF4 Q8WZA2 2/20 0.38
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
KDM4E B2RXH2 2/20 0.36
HPGD P15428 2/20 0.36
ALDH1A1 P00352 2/20 0.36
MAPT P10636 2/20 0.36
MAPK1 P28482 2/20 0.36
EGFR P00533 1/20 0.36
TP53 P04637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26303278 0.80 CES2 (0.46) CES2CES1F2PLGPLAU
SCHEMBL26303279 0.80 CES2 (0.46) CES2CES1F2PLGPLAU
SCHEMBL470757 0.80 CHRNB2 (0.38) KMT2AALDH1A1MAPTMAPK1ALOX15
SCHEMBL26303256 0.79 CES2 (0.44) CES2CES1F2PLGPLAU
SCHEMBL470761 0.78 CHRNB2 (0.35) F2PLGPLAUKLKB1PRSS1
SCHEMBL470756 0.74 MEN1 (0.35) MEN1KMT2ASMN1; SMN2KDM4EHPGD
SCHEMBL470759 0.74 ALDH1A1 (0.38) CES2CES1KMT2ASMN1; SMN2KDM4E
SCHEMBL470770 0.73 KDM4E (0.34) MEN1KMT2ASMN1; SMN2KDM4EHPGD
SCHEMBL470765 0.73 ALDH1A1 (0.34) CES2CES1KMT2ASMN1; SMN2KDM4E
SCHEMBL470758 0.72 MAPT (0.40) MEN1KMT2AKDM4EHPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140144509-A1 Compounds for Organic Photovoltaic Devices NOVALED AG (DE) 2014-05-29 US disclosed
WO-2012031735-A1 COMPOUNDS FOR ORGANIC PHOTOVOLTAIC DEVICES NOVALED AG (DE) 2012-03-15 WO disclosed