SCHEMBL470761

SCHEMBL470761

N#C/C(=C1/c2cc3ccccc3cc2-c2c1c1c(c3c2/C(=C(\C#N)c2ccccc2)c2cc4ccccc4cc2-3)/C(=C(\C#N)c2ccccc2)c2cc3ccccc3cc2-1)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 1/20 0.35
CHRNA4 P43681 1/20 0.35
ALDH1A1 P00352 3/20 0.31
MAPT P10636 2/20 0.31
F2 P00734 1/20 0.31
PLG P00747 1/20 0.31
PLAU P00749 1/20 0.31
KLKB1 P03952 1/20 0.31
PRSS1 P07477 1/20 0.31
NPC1 O15118 1/20 0.31
MAPK1 P28482 1/20 0.31
RAB9A P51151 1/20 0.31
PDE4A P27815 1/20 0.30
PDE4B Q07343 1/20 0.30
PDE4C Q08493 1/20 0.30
PDE4D Q08499 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL470770 0.88 KDM4E (0.34) ALDH1A1MAPTNPC1RAB9AMEN1
SCHEMBL470765 0.84 ALDH1A1 (0.34) ALDH1A1MAPTKMT2ATDP1KDM4E
SCHEMBL470757 0.82 CHRNB2 (0.38) CHRNB2CHRNA4ALDH1A1MAPTNPC1
SCHEMBL470766 0.79 ALDH1A1 (0.38) ALDH1A1MAPTMAPK1MEN1KMT2A
SCHEMBL470763 0.78 RAB9A (0.37) ALDH1A1MAPTNPC1MAPK1RAB9A
SCHEMBL470760 0.78 CES2 (0.41) ALDH1A1MAPTF2PLGPLAU
SCHEMBL470764 0.77 MAPT (0.47) ALDH1A1MAPTNPC1MAPK1RAB9A
SCHEMBL26303279 0.76 CES2 (0.46) CHRNB2CHRNA4ALDH1A1MAPTF2
SCHEMBL26303278 0.76 CES2 (0.46) CHRNB2CHRNA4ALDH1A1MAPTF2
SCHEMBL21125962 0.75 CHRNB2 (0.46) CHRNB2CHRNA4ALDH1A1MAPTF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140144509-A1 Compounds for Organic Photovoltaic Devices NOVALED AG (DE) 2014-05-29 US disclosed
WO-2012031735-A1 COMPOUNDS FOR ORGANIC PHOTOVOLTAIC DEVICES NOVALED AG (DE) 2012-03-15 WO disclosed