SCHEMBL470763

SCHEMBL470763

N#C/C(=C1/c2cc3ccccc3cc2-c2c1c1c(c3c2/C(=C(\C#N)c2cccs2)c2cc4ccccc4cc2-3)/C(=C(\C#N)c2cccs2)c2cc3ccccc3cc2-1)c1cccs1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 7/20 0.37
KMT2A Q03164 8/20 0.36
NPC1 O15118 7/20 0.36
MEN1 O00255 6/20 0.36
POLB P06746 4/20 0.35
MAPT P10636 2/20 0.35
ALDH1A1 P00352 1/20 0.35
ATM Q13315 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
ALOX15 P16050 1/20 0.35
MAPK1 P28482 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
HPGD P15428 3/20 0.34
ICMT O60725 1/20 0.34
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
EGFR P00533 1/20 0.33
ERBB2 P04626 1/20 0.33
LMNA P02545 1/20 0.33
GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL470762 0.84 CES2 (0.37) RAB9AKMT2ANPC1MEN1POLB
SCHEMBL470770 0.77 KDM4E (0.34) RAB9AKMT2ANPC1MEN1MAPT
SCHEMBL470766 0.74 ALDH1A1 (0.38) KMT2AMEN1MAPTALDH1A1MAPK1
SCHEMBL470765 0.73 ALDH1A1 (0.34) KMT2AMAPTALDH1A1SMN1; SMN2CES2
SCHEMBL470764 0.72 MAPT (0.47) RAB9AKMT2ANPC1MEN1POLB
SCHEMBL470760 0.67 CES2 (0.41) RAB9AKMT2ANPC1MEN1MAPT
SCHEMBL22109072 0.67 ALDH1A1 (0.33) MAPTALDH1A1GAA
SCHEMBL6188260 0.64 RAB9A (0.44) RAB9AKMT2ANPC1MEN1POLB
SCHEMBL29132008 0.64 ICMT (0.47) RAB9AKMT2ANPC1MEN1POLB
SCHEMBL11198155 0.64 CES2 (0.50) RAB9AKMT2ANPC1MEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140144509-A1 Compounds for Organic Photovoltaic Devices NOVALED AG (DE) 2014-05-29 US disclosed
WO-2012031735-A1 COMPOUNDS FOR ORGANIC PHOTOVOLTAIC DEVICES NOVALED AG (DE) 2012-03-15 WO disclosed