Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 8/20 | 0.50 |
| ▸ | CA2 | P00918 | 8/20 | 0.50 |
| ▸ | CA9 | Q16790 | 5/20 | 0.50 |
| ▸ | CA12 | O43570 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL789817 | 0.77 | NFE2L2 (0.52) | CA1CA2CA9CA12ALDH1A1 | |
| SCHEMBL29705304 | 0.77 | NFE2L2 (0.52) | CA1CA2CA9CA12ALDH1A1 | |
| SCHEMBL569758 | 0.77 | SOS1 (0.55) | CA1CA2CA9CA12SOS1 | |
| SCHEMBL14247634 | 0.75 | CA1 (0.51) | CA1CA2CA9CA12ALDH1A1 | |
| SCHEMBL4938450 | 0.74 | TDP1 (0.51) | ALDH1A1TDP1MAPK8HTR1ASLC6A2 | |
| SCHEMBL2329194 | 0.73 | MAPK8 (0.50) | ALDH1A1TDP1MAPK8HTR1ASLC6A2 | |
| SCHEMBL4008329 | 0.73 | PDE10A (0.51) | ALDH1A1TDP1MAPK8HTR1ASLC6A2 | |
| SCHEMBL2878935 | 0.73 | TDP1 (0.54) | ALDH1A1TDP1MAPK8HTR1ASLC6A2 | |
| SCHEMBL243134 | 0.73 | ALDH1A1 (0.53) | ALDH1A1TDP1MAPK8HTR1ASLC6A2 | |
| SCHEMBL10833920 | 0.71 | TDP1 (0.46) | ALDH1A1TDP1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879877-A2 | ANTIMICROBIAL AGENTS | Ranbaxy Laboratories Limited (IN) | 2008-01-23 | — | — | EP | claimed |
| WO-2006117762-A2 | ANTIMICROBIAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-11-09 | — | — | WO | claimed |
| EP-0103543-B1 | SULFONYL UREAS | CIBA-GEIGY AG (CH) | 1987-09-30 | — | — | EP | disclosed |
| US-4690707-A | PRE- AND POSTEMERGENCE HERBICIDES; PLANT GROWTH REGULATORS; PREFERENTIAL | CIBA-GEIGY CORPORATION (US) | 1987-09-01 | — | — | US | disclosed |
| US-4579583-A | HERBICIDES, GROWTH REGULATORS | CIBA-GEIGY CORPORATION (US) | 1986-04-01 | — | — | US | disclosed |
| EP-0103543-A2 | Sulfonyl ureas | CIBA-GEIGY AG (CH) | 1984-03-21 | — | — | EP | disclosed |