Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 10/20 | 0.50 |
| ▸ | CA1 | P00915 | 9/20 | 0.50 |
| ▸ | CA9 | Q16790 | 8/20 | 0.50 |
| ▸ | CA12 | O43570 | 6/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 3/20 | 0.47 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.47 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 3/20 | 0.47 |
| ▸ | CA4 | P22748 | 2/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.47 |
| ▸ | CA5A | P35218 | 2/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10529086 | 0.87 | CA2 (0.54) | SOS1CA2CA1CA9CA12 | |
| SCHEMBL3877575 | 0.85 | CASP1 (0.51) | SOS1CA2CA1CA9CA12 | |
| SCHEMBL10865382 | 0.85 | PTGES2 (0.57) | SOS1CA2CA1CA9CA12 | |
| SCHEMBL15258942 | 0.84 | SOS1 (0.47) | SOS1CA2CA1CA9CA12 | |
| SCHEMBL502864 | 0.83 | CASP1 (0.50) | SOS1CA2CA1CA9CASP1 | |
| SCHEMBL146565 | 0.83 | CASP1 (0.50) | SOS1CA2CA1CA9CASP1 | |
| SCHEMBL11599660 | 0.82 | CASP1 (0.49) | SOS1CA2CA1CA9CASP1 | |
| Ammonia Solution, Strong SCHEMBL502557 | 0.82 | CASP1 (0.49) | SOS1CA2CA1CA9CASP1 | |
| SCHEMBL4657647 | 0.81 | CA12 (0.55) | SOS1CA2CA1CA9CA12 | |
| SCHEMBL10865180 | 0.81 | CASP1 (0.55) | SOS1CA2CA1CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2393495-B1 | CARBAMOYLPHOSPHONATES AS INHIBITORS AND USES THEREOF | YISSUM RES DEV CO (IL) | 2014-07-23 | — | — | EP | claimed |
| US-20120035140-A1 | CARBAMOYLPHOSPHONATES AS INHIBITORS AND USES THEREOF | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM, LTD. (IL) | 2012-02-09 | — | — | US | claimed |
| EP-2393495-A1 | CARJBAMOYLPHOSPHONATES AS INHIBITORS AND USES THEREOF | Yissum Research Development Company of the Hebrew University of Jerusalem, Ltd. (IL) | 2011-12-14 | — | — | EP | claimed |
| WO-2010089752-A1 | CARJBAMOYLPHOSPHONATES AS INHIBITORS AND USES THEREOF | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM, LTD. (IL) | 2010-08-12 | — | — | WO | claimed |
| WO-2010039911-A1 | CALCILYTIC COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2010-04-08 | — | — | WO | claimed |
| CN-1103866-A | Nes pesticides | RHONE POULENC AGRICULTURE (GB) | 1995-06-21 | — | — | CN | claimed |
| EP-0634404-A1 | Phtalazin derivatives and their use as pesticides | RHONE POULENC AGRICULTURE LTD. (GB) | 1995-01-18 | — | — | EP | claimed |
| EP-0148755-B1 | 2-PHENOXY-PHENYLSULFONYLISOCYANATE | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-11-20 | — | — | EP | claimed |
| EP-0148755-A2 | 2-Phenoxy-phenylsulfonylisocyanate | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1985-07-17 | — | — | EP | claimed |
| US-20260062393-A1 | Compounds | CTXT PTY LTD (AU) | 2026-03-05 | — | — | US | disclosed |
| US-12365655-B2 | Compounds | CTXT PTY LTD (AU) | 2025-07-22 | — | — | US | disclosed |
| US-20220153710-A1 | Compounds | CTXT PTY LTD (AU) | 2022-05-19 | — | — | US | disclosed |
| US-9206130-B2 | Quinoline derivatives as AXL kinase inhibitors | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2015-12-08 | — | — | US | disclosed |
| US-8993544-B2 | Carbamoylphosphonates as inhibitors and uses thereof | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM, LTD. (IL) | 2015-03-31 | — | — | US | disclosed |
| EP-0148755-A2 | 2-Phenoxy-phenylsulfonylisocyanate | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1985-07-17 | — | — | EP | disclosed |
| EP-0148755-A2 | 2-Phenoxy-phenylsulfonylisocyanate | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1985-07-17 | — | — | EP | disclosed |
| US-4514213-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-04-30 | — | — | US | disclosed |
| US-4500342-A | Herbicidally active substituted phenylsulfonylurea derivatives and intermediates therefor | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1985-02-19 | — | — | US | disclosed |
| EP-0129764-A2 | Substituted phenylsulfonyl guanidine derivatives | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1985-01-02 | — | — | EP | disclosed |
| EP-0056969-A2 | Substituted derivatives of phenylsulfonyl urea, process and intermediates for their preparation and herbicidal compositions containing the derivatives | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1982-08-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120035140-A1 | CARBAMOYLPHOSPHONATES AS INHIBITORS AND USES THEREOF | MMP9, MMP26, MMP25 | SOS1 3731/4885CA2 91/4885CA1 247/4885 |
| US-20220153710-A1 | Compounds | SLC10A1, ABCB11, PCSK9 | SOS1 2530/4885CA2 255/4885CA1 881/4885 |
| US-20260062393-A1 | Compounds | SCN2B, ABCB11, SCN1B | SOS1 4066/4885CA2 199/4885CA1 1778/4885 |
| US-12365655-B2 | Compounds | SLC10A1, ABCB11, PCSK9 | SOS1 2526/4885CA2 256/4885CA1 881/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.