Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.64 |
| ▸ | KDM1A | O60341 | 1/20 | 0.62 |
| ▸ | HTR1A | P08908 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | DRD2 | P14416 | 1/20 | 0.57 |
| ▸ | DRD3 | P35462 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4715710 | 0.87 | HTR1A (0.68) | MAOBHTR1AALDH1A1DRD2DRD3 | |
| SCHEMBL13469510 | 0.86 | HTR1A (0.79) | MAOBHTR1ADRD2DRD3 | |
| SCHEMBL1275567 | 0.84 | HTR1A (0.68) | MAOBHTR1AALDH1A1DRD2DRD3 | |
| SCHEMBL10850210 | 0.84 | MAOB (0.59) | MAOBHTR1AALDH1A1DRD2DRD3 | |
| SCHEMBL7972938 | 0.83 | ALDH1A1 (0.70) | MAOBHTR1AALDH1A1DRD2 | |
| SCHEMBL1532232 | 0.83 | MAOB (0.73) | MAOBHTR1ADRD2DRD3 | |
| SCHEMBL14028451 | 0.83 | HTR1A (0.79) | MAOBHTR1ADRD2DRD3 | |
| SCHEMBL10857215 | 0.82 | HTR1A (0.68) | MAOBHTR1ADRD2DRD3 | |
| SCHEMBL6946848 | 0.82 | MAOB (0.71) | MAOBHTR1ADRD2DRD3 | |
| SCHEMBL17844904 | 0.82 | DRD2 (0.56) | MAOBHTR1AALDH1A1DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1991528-A2 | MODULATORS OF ALPHA7 NICOTINIC ACETYLCHOLINE RECEPTORS AND THERAPEUTIC USES THEREOF | Siena Biotech S.p.A. (IT) | 2008-11-19 | — | — | EP | disclosed |
| WO-2007098826-A2 | MODULATORS OF ALPHA7 NICOTINIC ACETYLCHOLINE RECEPTORS AND THERAPEUTIC USES THEREOF | SIENA BIOTECH S.P.A. (IT) | 2007-09-07 | — | — | WO | disclosed |