Sugi Predict

Sugi Predict / Compounds / SCHEMBL471006

SCHEMBL471006

SCHEMBL471006

C/C=C\c1cccc(OC)c1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RELA Q04206 1/20 0.69
▸ NFE2L2 Q16236 4/20 0.65
▸ CYP19A1 P11511 1/20 0.62
▸ NQO2 P16083 1/20 0.62
▸ TUBB4A P04350 1/20 0.61
▸ TUBB P07437 1/20 0.61
▸ TUBA3C P0DPH7 1/20 0.61
▸ TUBA1B P68363 1/20 0.61
▸ TUBA4A P68366 1/20 0.61
▸ TUBB4B P68371 1/20 0.61
▸ TUBB3 Q13509 1/20 0.61
▸ TUBB2A Q13885 1/20 0.61
▸ TUBB8 Q3ZCM7 1/20 0.61
▸ TUBA3E Q6PEY2 1/20 0.61
▸ TUBA1A Q71U36 1/20 0.61
▸ TUBA1C Q9BQE3 1/20 0.61
▸ TUBB6 Q9BUF5 1/20 0.61
▸ TUBB2B Q9BVA1 1/20 0.61
▸ TUBB1 Q9H4B7 1/20 0.61
▸ CHRM5 P08912 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL257114 1.00 RELA (0.69) RELANFE2L2CYP19A1NQO2TUBB4A
SCHEMBL7194475 1.00 RELA (0.69) RELANFE2L2CYP19A1NQO2TUBB4A
SCHEMBL31317665 0.89 RELA (0.84) RELANFE2L2CYP19A1NQO2TUBB4A
SCHEMBL700056 0.89 RELA (0.84) RELANFE2L2CYP19A1NQO2TUBB4A
SCHEMBL700055 0.89 RELA (0.84) RELANFE2L2CYP19A1NQO2TUBB4A
SCHEMBL23158820 0.89 RELA (0.84) RELANFE2L2CYP19A1NQO2TUBB4A
SCHEMBL15932972 0.86 RELA (0.62) RELANFE2L2CYP19A1NQO2TUBB4A
SCHEMBL14401251 0.83 RELA (0.81) RELANFE2L2CYP19A1NQO2TUBB4A
SCHEMBL700797 0.83 RELA (0.81) RELANFE2L2CYP19A1NQO2TUBB4A
SCHEMBL700798 0.83 RELA (0.81) RELANFE2L2CYP19A1NQO2TUBB4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10071067-B2 Anise flavored medication THE PROCTER & GAMBLE COMPANY (US) 2018-09-11 — — US claimed
US-20180064661-A1 Anise Flavored Medication PROCTER & GAMBLE (US) 2018-03-08 — — US claimed
US-9839620-B2 Anise flavored medication THE PROCTER & GAMBLE COMPANY (US) 2017-12-12 — — US claimed
US-20160361277-A1 Anise Flavored Medication PROCTER & GAMBLE (US) 2016-12-15 — — US claimed
US-10588872-B2 Anise flavored medication THE PROCTER & GAMBLE COMPANY (US) 2020-03-17 — — US disclosed
CN-105802925-B A kind of CYP119 enzyme mutant and its application 西南医科大学 2019-06-25 — — CN disclosed
US-20180344670-A1 Anise Flavored Medication PROCTER & GAMBLE (US) 2018-12-06 — — US disclosed
US-10071067-B2 Anise flavored medication THE PROCTER & GAMBLE COMPANY (US) 2018-09-11 — — US disclosed
US-20180064661-A1 Anise Flavored Medication PROCTER & GAMBLE (US) 2018-03-08 — — US disclosed
US-9839620-B2 Anise flavored medication THE PROCTER & GAMBLE COMPANY (US) 2017-12-12 — — US disclosed
US-20170037059-A1 GYRASE INHIBITORS MERCK SHARP & DOHME CORP. (US) 2017-02-09 — — US disclosed
US-20160361277-A1 Anise Flavored Medication PROCTER & GAMBLE (US) 2016-12-15 — — US disclosed
WO-2014127118-A1 ANISE FLAVORED MEDICATION THE PROCTER & GAMBLE COMPANY (US) 2014-08-21 — — WO disclosed
US-20140228391-A1 Anise Flavored Medication THE PROCTER & GAMBLE COMPANY (US) 2014-08-14 — — US disclosed
US-20130079323-A1 GYRASE INHIBITORS TRIUS THERAPEUTICS, INC. (US) 2013-03-28 — — US disclosed
WO-2012031358-A1 BIARYL DIPHOSPHINE LIGANDS, INTERMEDIATES OF THE SAME AND THEIR USE IN ASYMMETRIC CATALYSIS KANATA CHEMICAL TECHNOLOGIES INC. (CA) 2012-03-15 — — WO disclosed
US-20110009447-A1 Substituted Benzoic Acid Amides and Use thereof for the Inhibition of Angiogenesis SCHERING AG (DE) 2011-01-13 — — US disclosed
US-20110009447-A1 Substituted Benzoic Acid Amides and Use thereof for the Inhibition of Angiogenesis SCHERING AG (DE) 2011-01-13 — — US disclosed
EP-1280776-B1 SUBSTITUTED BENZOIC ACID AMIDES AND USE THEREOF FOR THE INHIBITION OF ANGIOGENESIS BAYER SCHERING PHARMA AG (DE) 2009-10-21 — — EP disclosed
US-6613317-B1 In particular northern corn rootworm THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS 2003-09-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170037059-A1 GYRASE INHIBITORS TOP1, CA7, TOP2B RELA 1542/4885NFE2L2 3680/4885CYP19A1 1293/4885
US-20180344670-A1 Anise Flavored Medication ADRB1, ADRA1B, ADRA2B RELA 1231/4885NFE2L2 1241/4885CYP19A1 2900/4885
US-20160361277-A1 Anise Flavored Medication ADRB1, ADRA1B, ADRA2B RELA 1231/4885NFE2L2 1241/4885CYP19A1 2900/4885
US-10071067-B2 Anise flavored medication ADRB1, ADRA1B, ADRA2B RELA 1231/4885NFE2L2 1241/4885CYP19A1 2900/4885
US-20130079323-A1 GYRASE INHIBITORS TOP1, CA7, TOP2B RELA 1542/4885NFE2L2 3680/4885CYP19A1 1293/4885
US-20180064661-A1 Anise Flavored Medication ADRB1, ADRA1B, ADRA2B RELA 1231/4885NFE2L2 1241/4885CYP19A1 2900/4885
US-10588872-B2 Anise flavored medication ADRB1, ADRA1B, ADRA2B RELA 1231/4885NFE2L2 1241/4885CYP19A1 2900/4885
US-20140228391-A1 Anise Flavored Medication ADRB1, ADRA1B, ADRA2B RELA 1231/4885NFE2L2 1241/4885CYP19A1 2900/4885
US-20110009447-A1 Substituted Benzoic Acid Amides and Use thereof for the Inhibition of Angiogenesis VEGFA, EGLN2, HIF1AN RELA 342/4885NFE2L2 324/4885CYP19A1 51/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.