Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | TRPC3 | Q13507 | 2/20 | 0.32 |
| ▸ | TRPC6 | Q9Y210 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15070484 | 0.78 | RIPK1 (0.50) | HPGDRAB9ASMN1; SMN2HTTAPOBEC3A | |
| SCHEMBL19152335 | 0.65 | HRH3 (0.48) | HPGDRAB9ASMN1; SMN2HTTKDM4E | |
| SCHEMBL14375269 | 0.62 | ALDH1A1 (0.49) | ALDH1A1ACHE | |
| SCHEMBL2722252 | 0.61 | POLB (0.48) | KDM4ERIPK1PKMALDH1A1POLB | |
| SCHEMBL13974870 | 0.59 | NAMPT (0.50) | HPGDRAB9ASMN1; SMN2KDM4ERIPK1 | |
| SCHEMBL13744784 | 0.57 | L3MBTL1 (0.73) | HPGDRAB9ASMN1; SMN2RIPK1TRPC3 | |
| SCHEMBL19937938 | 0.57 | QDPR (0.43) | KDM4EALDH1A1MAPTPOLB | |
| SCHEMBL17546317 | 0.57 | CYP3A4 (0.53) | HPGDAPOBEC3AAPOBEC3GALDH1A1ACHE | |
| SCHEMBL770867 | 0.57 | ALDH1A1 (0.54) | HPGDRAB9ASMN1; SMN2APOBEC3AAPOBEC3G | |
| SCHEMBL10660097 | 0.56 | ALDH1A1 (0.50) | HPGDRAB9ASMN1; SMN2ALDH1A1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012033069-A1 | PROSTAGLANDIN D SYNTHASE INHIBITORY PIPERIDINE COMPOUNDS | 大鵬薬品工業株式会社 (JP) | 2012-03-15 | — | — | WO | disclosed |