Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | CPA1 | P15085 | 1/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL4714104 | 0.87 | CYP3A4 (0.38) | CETPALDH1A1CA2CYP3A4PTGES | |
| Phosphoric Acid SCHEMBL4713921 | 0.84 | ALDH1A1 (0.43) | CETPALDH1A1MMEACECPA1 | |
| Phosphoric Acid SCHEMBL4712956 | 0.83 | L3MBTL1 (0.44) | ALDH1A1CA2CYP3A4PPARAPTGES | |
| Phosphoric Acid SCHEMBL4710580 | 0.81 | ALDH1A1 (0.35) | ALDH1A1CA2CYP3A4LMNA | |
| Phosphoric Acid SCHEMBL4714969 | 0.81 | CETP (0.48) | CETP | |
| Phosphoric Acid SCHEMBL4712516 | 0.81 | CETP (0.48) | CETP | |
| Phosphoric Acid SCHEMBL4709476 | 0.81 | CETP (0.48) | CETP | |
| Phosphoric Acid SCHEMBL4711876 | 0.81 | CETP (0.48) | CETP | |
| Phosphoric Acid SCHEMBL4709390 | 0.81 | CETP (0.48) | CETP | |
| Phosphoric Acid SCHEMBL4711372 | 0.80 | PRSS1 (0.39) | ALDH1A1CA2CYP3A4PTGESALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3279406-A1 | FLAME-RETARDANT FLOOR MATERIAL AND METHOD FOR MANUFACTURING SAME | LG Hausys, Ltd. (KR) | 2018-02-07 | — | — | EP | disclosed |
| US-20170043558-A1 | A FLAME RETARDANT FLOORING MATERIAL AND METHOD OF MANUFACTURING THE SAME | LG HAUSYS, LTD. (KR) | 2017-02-16 | — | — | US | disclosed |
| EP-1809474-B1 | FIRE RESISTANT POLYMER SHEETS | SOLUTIA INC (US) | 2016-05-11 | — | — | EP | disclosed |
| US-7399525-B2 | Between two glass panes a multilayer interlayer conposed of a fluoropolymer sheet (hexafluoropropylene-tetrafluoroethylene-vinylidene fluoro terpolymer) having a thickness of 0.1 to 1.5 millimeters and a polyvinyl butyral polymer sheet; fire resistance | SOLUTIA INCORPORATED (US) | 2008-07-15 | — | — | US | disclosed |
| US-7279516-B2 | Polymer sheets comprising higher order phosphate esters | SOLUTIA INCORPORATED (US) | 2007-10-09 | — | — | US | disclosed |
| EP-1809474-A1 | FIRE RESISTANT POLYMER SHEETS | Solutia Inc. (US) | 2007-07-25 | — | — | EP | disclosed |
| US-7238427-B2 | Fire resistant polymer sheets | SOLUTIA INCORPORATED (US) | 2007-07-03 | — | — | US | disclosed |
| WO-2006098777-A1 | POLYMER SHEETS COMPRISING HIGHER ORDER PHOSPHATE ESTERS | SOLUTIA INCORPORATED (US) | 2006-09-21 | — | — | WO | disclosed |
| WO-2006050218-A1 | POLYMER SHEETS COMPRISING A FLUOROPOLYMER | SOLUTIA INCORPORATED (US) | 2006-05-11 | — | — | WO | disclosed |
| WO-2006050216-A1 | FIRE RESISTANT POLYMER SHEETS | SOLUTIA INCORPORATED (US) | 2006-05-11 | — | — | WO | disclosed |
| US-20060093830-A1 | Polymer sheets comprising a fluoropolymer | SOLUTIA, INC. | 2006-05-04 | — | — | US | disclosed |
| US-20060094803-A1 | Polymer sheets comprising higher order phosphate esters | SOLUTIA, INC. | 2006-05-04 | — | — | US | disclosed |
| US-20060093832-A1 | Fire resistant polymer sheets | SOLUTIA INC. | 2006-05-04 | — | — | US | disclosed |