Phosphoric Acid

Phosphoric Acid

SCHEMBL4710580

CCCCC(CC)Cc1cc(C)ccc1OC(C)CC.O=P(O)(O)O

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.35
MAPK1 P28482 3/20 0.35
L3MBTL1 Q9Y468 4/20 0.35
CYP3A4 P08684 3/20 0.35
CA2 P00918 1/20 0.34
PDE10A Q9Y233 1/20 0.34
TSHR P16473 4/20 0.34
GLA P06280 1/20 0.34
HTT P42858 1/20 0.34
FFAR1 O14842 1/20 0.32
FFAR4 Q5NUL3 1/20 0.32
LMNA P02545 2/20 0.32
GAA P10253 2/20 0.32
MAPT P10636 1/20 0.32
THRB P10828 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
HSD17B10 Q99714 1/20 0.32
NR1I2 O75469 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL4712956 0.85 L3MBTL1 (0.44) ALDH1A1MAPK1L3MBTL1CYP3A4CA2
Phosphoric Acid SCHEMBL4711503 0.81 CETP (0.40) ALDH1A1CYP3A4CA2LMNA
Phosphoric Acid SCHEMBL4711372 0.81 PRSS1 (0.39) ALDH1A1MAPK1L3MBTL1CYP3A4CA2
SCHEMBL6065377 0.77 ALDH1A1 (0.49) ALDH1A1MAPK1L3MBTL1TSHRHTT
SCHEMBL2150099 0.74 ALDH1A1 (0.41) ALDH1A1MAPK1L3MBTL1CYP3A4CA2
Phosphoric Acid SCHEMBL27973641 0.74 L3MBTL1 (0.41) ALDH1A1L3MBTL1CYP3A4CA2TSHR
SCHEMBL1656307 0.74 SRC (0.40) ALDH1A1MAPK1L3MBTL1CYP3A4CA2
SCHEMBL7530042 0.73 NR3C1 (0.43) ALDH1A1MAPK1L3MBTL1CYP3A4CA2
SCHEMBL22916144 0.71 CYP3A4 (0.41) ALDH1A1MAPK1L3MBTL1CYP3A4PDE10A
Phosphoric Acid SCHEMBL15475371 0.71 TSHR (0.37) ALDH1A1MAPK1L3MBTL1CYP3A4CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3279406-A1 FLAME-RETARDANT FLOOR MATERIAL AND METHOD FOR MANUFACTURING SAME LG Hausys, Ltd. (KR) 2018-02-07 EP disclosed
US-20170043558-A1 A FLAME RETARDANT FLOORING MATERIAL AND METHOD OF MANUFACTURING THE SAME LG HAUSYS, LTD. (KR) 2017-02-16 US disclosed
EP-1809474-B1 FIRE RESISTANT POLYMER SHEETS SOLUTIA INC (US) 2016-05-11 EP disclosed
US-7399525-B2 Between two glass panes a multilayer interlayer conposed of a fluoropolymer sheet (hexafluoropropylene-tetrafluoroethylene-vinylidene fluoro terpolymer) having a thickness of 0.1 to 1.5 millimeters and a polyvinyl butyral polymer sheet; fire resistance SOLUTIA INCORPORATED (US) 2008-07-15 US disclosed
US-7279516-B2 Polymer sheets comprising higher order phosphate esters SOLUTIA INCORPORATED (US) 2007-10-09 US disclosed
EP-1809474-A1 FIRE RESISTANT POLYMER SHEETS Solutia Inc. (US) 2007-07-25 EP disclosed
US-7238427-B2 Fire resistant polymer sheets SOLUTIA INCORPORATED (US) 2007-07-03 US disclosed
WO-2006098777-A1 POLYMER SHEETS COMPRISING HIGHER ORDER PHOSPHATE ESTERS SOLUTIA INCORPORATED (US) 2006-09-21 WO disclosed
WO-2006050218-A1 POLYMER SHEETS COMPRISING A FLUOROPOLYMER SOLUTIA INCORPORATED (US) 2006-05-11 WO disclosed
WO-2006050216-A1 FIRE RESISTANT POLYMER SHEETS SOLUTIA INCORPORATED (US) 2006-05-11 WO disclosed
US-20060093830-A1 Polymer sheets comprising a fluoropolymer SOLUTIA, INC. 2006-05-04 US disclosed
US-20060094803-A1 Polymer sheets comprising higher order phosphate esters SOLUTIA, INC. 2006-05-04 US disclosed
US-20060093832-A1 Fire resistant polymer sheets SOLUTIA INC. 2006-05-04 US disclosed