Phosphoric Acid

Phosphoric Acid

SCHEMBL4711372

CCCCCCC(CCCC)COc1ccc(C)cc1CC(CC)CCCC.O=P(O)(O)O

nearest known ligand 0.39

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRSS1 P07477 1/20 0.39
PRSS2 P07478 1/20 0.39
PRSS3 P35030 1/20 0.39
ALDH1A1 P00352 5/20 0.38
MAPK1 P28482 3/20 0.38
GAA P10253 2/20 0.38
MAPT P10636 2/20 0.38
THRB P10828 2/20 0.38
NPSR1 Q6W5P4 1/20 0.38
L3MBTL1 Q9Y468 3/20 0.36
CYP3A4 P08684 2/20 0.36
CA2 P00918 1/20 0.36
ENPP2 Q13822 1/20 0.35
FDPS P14324 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
TSHR P16473 1/20 0.35
GPR55 Q9Y2T6 1/20 0.34
SMPD1 P17405 3/20 0.33
S1PR1 P21453 2/20 0.33
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL4712956 0.88 L3MBTL1 (0.44) ALDH1A1MAPK1GAAMAPTTHRB
SCHEMBL2150099 0.84 ALDH1A1 (0.41) PRSS1PRSS2PRSS3ALDH1A1MAPK1
Phosphoric Acid SCHEMBL4710580 0.81 ALDH1A1 (0.35) ALDH1A1MAPK1GAAMAPTTHRB
SCHEMBL6065377 0.80 ALDH1A1 (0.49) ALDH1A1MAPK1GAAMAPTTHRB
Phosphoric Acid SCHEMBL4711503 0.80 CETP (0.40) ALDH1A1CYP3A4CA2LMNAPTGES
SCHEMBL9846312 0.75 AMY1A (0.41) PRSS1PRSS2PRSS3MAPTCYP3A4
Phosphoric Acid SCHEMBL10596243 0.73 MAPT (0.53) ALDH1A1MAPK1GAAMAPTTHRB
Phosphoric Acid SCHEMBL9818193 0.73 MAPT (0.53) ALDH1A1MAPK1GAAMAPTTHRB
Phosphoric Acid SCHEMBL11323353 0.73 MAPT (0.53) ALDH1A1MAPK1GAAMAPTTHRB
SCHEMBL6114500 0.73 S1PR1 (0.37) PRSS1PRSS2PRSS3ALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3279406-A1 FLAME-RETARDANT FLOOR MATERIAL AND METHOD FOR MANUFACTURING SAME LG Hausys, Ltd. (KR) 2018-02-07 EP disclosed
US-20170043558-A1 A FLAME RETARDANT FLOORING MATERIAL AND METHOD OF MANUFACTURING THE SAME LG HAUSYS, LTD. (KR) 2017-02-16 US disclosed
EP-1809474-B1 FIRE RESISTANT POLYMER SHEETS SOLUTIA INC (US) 2016-05-11 EP disclosed
US-7399525-B2 Between two glass panes a multilayer interlayer conposed of a fluoropolymer sheet (hexafluoropropylene-tetrafluoroethylene-vinylidene fluoro terpolymer) having a thickness of 0.1 to 1.5 millimeters and a polyvinyl butyral polymer sheet; fire resistance SOLUTIA INCORPORATED (US) 2008-07-15 US disclosed
US-7279516-B2 Polymer sheets comprising higher order phosphate esters SOLUTIA INCORPORATED (US) 2007-10-09 US disclosed
EP-1809474-A1 FIRE RESISTANT POLYMER SHEETS Solutia Inc. (US) 2007-07-25 EP disclosed
US-7238427-B2 Fire resistant polymer sheets SOLUTIA INCORPORATED (US) 2007-07-03 US disclosed
WO-2006098777-A1 POLYMER SHEETS COMPRISING HIGHER ORDER PHOSPHATE ESTERS SOLUTIA INCORPORATED (US) 2006-09-21 WO disclosed
WO-2006050218-A1 POLYMER SHEETS COMPRISING A FLUOROPOLYMER SOLUTIA INCORPORATED (US) 2006-05-11 WO disclosed
WO-2006050216-A1 FIRE RESISTANT POLYMER SHEETS SOLUTIA INCORPORATED (US) 2006-05-11 WO disclosed
US-20060093830-A1 Polymer sheets comprising a fluoropolymer SOLUTIA, INC. 2006-05-04 US disclosed
US-20060094803-A1 Polymer sheets comprising higher order phosphate esters SOLUTIA, INC. 2006-05-04 US disclosed
US-20060093832-A1 Fire resistant polymer sheets SOLUTIA INC. 2006-05-04 US disclosed