Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1556224 | 0.77 | DAO (0.35) | AURKAAURKBINCENPDAOHDAC8 | |
| SCHEMBL5405555 | 0.74 | DAO (0.33) | AURKAAURKBINCENPDAOHDAC8 | |
| SCHEMBL31512727 | 0.72 | — | — | |
| SCHEMBL15914861 | 0.70 | HDAC8 (0.36) | AURKAAURKBINCENPDAOHDAC8 | |
| SCHEMBL5402727 | 0.69 | LTA4H (0.31) | TSHR | |
| SCHEMBL1557675 | 0.67 | CYP3A4 (0.50) | FKBP5 | |
| SCHEMBL15364239 | 0.67 | — | — | |
| SCHEMBL1557189 | 0.67 | CYP3A4 (0.50) | FKBP5 | |
| SCHEMBL31522791 | 0.66 | — | — | |
| SCHEMBL16041245 | 0.64 | DAO (0.31) | DAOHDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115785156-A | Naphthalimide functionalized phosphine ligand and preparation method thereof | 四川大学 | 2023-03-14 | — | — | CN | claimed |
| CN-110343209-B | Bidentate phosphorus ligand polymer, preparation method thereof and application thereof in olefin hydroformylation reaction | 中国科学院青岛生物能源与过程研究所 | 2021-09-17 | — | — | CN | claimed |
| CN-115785156-A | Naphthalimide functionalized phosphine ligand and preparation method thereof | 四川大学 | 2023-03-14 | — | — | CN | disclosed |
| CN-113004326-B | Phosphine ligand for butadiene hydroformylation reaction and preparation method thereof | 中国科学院青岛生物能源与过程研究所 | 2022-11-04 | — | — | CN | disclosed |
| CN-114891036-A | Process for preparing phosphorus-containing ligands | 浙江新和成股份有限公司 | 2022-08-12 | — | — | CN | disclosed |
| CN-110343209-B | Bidentate phosphorus ligand polymer, preparation method thereof and application thereof in olefin hydroformylation reaction | 中国科学院青岛生物能源与过程研究所 | 2021-09-17 | — | — | CN | disclosed |
| EP-1789185-B2 | PHSPHORUS-CONTAINING CATALYST COMPOSITION AND PROCESS FOR HYDROFORMYLATION USING THE SAME | LG CHEMICAL LTD (KR) | 2018-07-25 | — | — | EP | disclosed |
| US-9795952-B2 | Bidentate ligands for hydroformylation of ethylene | DOW TECHNOLOGY INVESTMENTS LLC (US) | 2017-10-24 | — | — | US | disclosed |
| US-20150328628-A1 | Bidentate Ligands for Hydroformylation of Ethylene | THE DOW CHEMICAL COMPANY | 2015-11-19 | — | — | US | disclosed |
| EP-1789185-B1 | PHSPHORUS-CONTAINING CATALYST COMPOSITION AND PROCESS FOR HYDROFORMYLATION USING THE SAME | LG CHEMICAL LTD (KR) | 2015-03-04 | — | — | EP | disclosed |
| WO-2014088800-A1 | BIDENTATE LIGANDS FOR HYDROFORMYLATION OF ETHYLENE | DOW TECHNOLOGY INVESTMENTS LLC (US) | 2014-06-12 | — | — | WO | disclosed |
| EP-2740535-A1 | Bidentate ligands for hydroformylation of ethylene | Dow Technology Investments LLC (US) | 2014-06-11 | — | — | EP | disclosed |
| EP-1789185-A4 | PHSPHORUS-CONTAINING CATALYST COMPOSITION AND PROCESS FOR HYDROFORMYLATION USING THE SAME | LG CHEMICAL LTD (KR) | 2008-12-31 | — | — | EP | disclosed |
| US-7425656-B2 | Phosphorus-containing catalyst composition and process for hydroformylation reaction using the same | LG CHEM, LTD (KR) | 2008-09-16 | — | — | US | disclosed |
| EP-1789185-A1 | PHSPHORUS-CONTAINING CATALYST COMPOSITION AND PROCESS FOR HYDROFORMYLATION USING THE SAME | LG Chem, Ltd. (KR) | 2007-05-30 | — | — | EP | disclosed |
| US-7173138-B2 | Ligands for pnicogen chelate complexes with a metal of subgroup VIII and use of the complexes as catalysts for hydroformylation, carbonylation, hydrocyanation or hydrogenation | BASF AKTIENGESELLSCHAFT (DE) | 2007-02-06 | — | — | US | disclosed |
| WO-2006031068-A1 | PHSPHORUS-CONTAINING CATALYST COMPOSITION AND PROCESS FOR HYDROFORMYLATION USING THE SAME | LG CHEM, LTD. (KR) | 2006-03-23 | — | — | WO | disclosed |
| US-20060058558-A1 | Phsphorus-containing catalyst composition and process for hydroformylation reaction using the same | LG CHEM. LTD. (KR) | 2006-03-16 | — | — | US | disclosed |
| US-20040110960-A1 | Ligands for pnicogen chelate complexes with a metal of subgroup VIII and use of the complexes as catalysts for hydroformylation, carbonylation, hydrocyanation or hydrogenation | BASF AKTIENGESELLSCHAFT (DE) | 2004-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110960-A1 | Ligands for pnicogen chelate complexes with a metal of subgroup VIII and use of the complexes as catalysts for hydroformylation, carbonylation, hydrocyanation or hydrogenation | OGG1, HPD, HPGD | AURKA 2696/4885AURKB 3364/4885INCENP 2760/4885 |
| US-20060058558-A1 | Phsphorus-containing catalyst composition and process for hydroformylation reaction using the same | NUDT1, HMOX1, HPD | AURKA 2203/4885AURKB 3689/4885INCENP 1354/4885 |
| US-20150328628-A1 | Bidentate Ligands for Hydroformylation of Ethylene | HRH4, HRH3, H1-4 | AURKA 3710/4885AURKB 3983/4885INCENP 4533/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.