Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 3/20 | 0.38 |
| ▸ | ACHE | P22303 | 3/20 | 0.38 |
| ▸ | QPCT | Q16769 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4714453 | 0.88 | ALDH1A1 (0.41) | THRATHRBALDH1A1LMNACYP1A2 | |
| SCHEMBL4715746 | 0.87 | ALDH1A1 (0.44) | ALDH1A1HSD17B10CYP1A2MAPTKMT2A | |
| SCHEMBL4712830 | 0.86 | ALDH1A1 (0.39) | THRATHRBALDH1A1LMNACYP1A2 | |
| SCHEMBL4714324 | 0.85 | THRA (0.39) | HPGDTHRATHRBALDH1A1BCHE | |
| SCHEMBL7349972 | 0.76 | ALDH1A1 (0.46) | ALDH1A1LMNACYP1A2GAA | |
| SCHEMBL7348551 | 0.73 | KDM4E (0.42) | THRATHRBALDH1A1LMNACYP1A2 | |
| SCHEMBL4715224 | 0.73 | ALDH1A1 (0.40) | THRATHRBALDH1A1LMNACYP1A2 | |
| SCHEMBL4717150 | 0.72 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL4710572 | 0.72 | THRA (0.37) | HPGDTHRATHRBALDH1A1LMNA | |
| SCHEMBL4710329 | 0.68 | CYP1A2 (0.46) | CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0998459-B1 | PYRIDINE DERIVATIVES | NOVARTIS AG (CH) | 2008-04-23 | — | — | EP | disclosed |