Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 2/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.43 |
| ▸ | MYC | P01106 | 2/20 | 0.42 |
| ▸ | MAX | P61244 | 2/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | PELP1 | Q8IZL8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27613391 | 0.91 | XDH (0.48) | XDHPRSS1MYCMAXAR | |
| SCHEMBL4718483 | 0.81 | XDH (0.47) | XDHPRSS1MYCMAXAR | |
| SCHEMBL28451159 | 0.77 | MYC (0.58) | PRSS1MYCMAXARPELP1 | |
| SCHEMBL17395859 | 0.76 | ALDH1A1 (0.59) | XDHPRSS1MYCMAXAR | |
| SCHEMBL4717487 | 0.76 | MYC (0.64) | XDHPRSS1MYCMAX | |
| SCHEMBL2810372 | 0.75 | AR (0.49) | XDHPRSS1MYCMAXAR | |
| SCHEMBL4716592 | 0.75 | MYC (0.51) | XDHMYCMAXARPELP1 | |
| SCHEMBL4717489 | 0.75 | PDK1 (0.52) | XDHPRSS1MYCMAXAR | |
| SCHEMBL4718892 | 0.74 | AR (0.67) | XDHMYCMAXARPELP1 | |
| SCHEMBL2773030 | 0.74 | AR (0.55) | XDHPRSS1MYCMAXAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1452528-B1 | XANTHINE OXIDASE INHIBITORS | NIPPON CHEMIPHAR CO (JP) | 2008-08-13 | — | — | EP | disclosed |
| CN-101092400-A | Xanthine oxidase inhibitor | NIPPON CHEMIPHAR CO (JP) | 2007-12-26 | — | — | CN | disclosed |
| CN-100338040-C | xanthine oxidase inhibiting compounds | NIPPON CHEMIPHAR CO (JP) | 2007-09-19 | — | — | CN | disclosed |
| CN-1615299-A | Xanthine oxidase inhibitors | NIPPON CHEMIPHAR CO (JP) | 2005-05-11 | — | — | CN | disclosed |
| EP-1452528-A1 | XANTHINE OXIDASE INHIBITORS | NIPPON CHEMIPHAR CO., LTD. (JP) | 2004-09-01 | — | — | EP | disclosed |