Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.52 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.52 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.52 |
| ▸ | TRPV4 | Q9HBA0 | 3/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.42 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 4/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL101711 | 0.82 | TRPV4 (0.61) | TRPV4CYP11B2VCAM1ARMRGPRX4 | |
| SCHEMBL2198533 | 0.78 | CYP11B2 (0.46) | TRPV4CYP11B2VCAM1ARCYP11B1 | |
| Dichlobenil SCHEMBL28814465 | 0.76 | KDM4E (0.46) | TAS1R3TAS1R1TAS1R2TRPV4 | |
| SCHEMBL186269 | 0.75 | ALDH1A1 (0.50) | TAS1R3TAS1R1TAS1R2TRPV4 | |
| SCHEMBL5711187 | 0.75 | CYP11B2 (0.54) | TRPV4CYP11B2ARCYP11B1 | |
| SCHEMBL496891 | 0.74 | TRPV4 (0.57) | TRPV4CYP11B2VCAM1CYP11B1MAOA | |
| SCHEMBL186023 | 0.74 | KDM4E (0.47) | TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL3338599 | 0.72 | AR (0.43) | TRPV4CYP11B2ARCYP11B1 | |
| SCHEMBL29998893 | 0.72 | CYP2A6 (0.46) | TRPV4CYP11B2VCAM1ARCYP11B1 | |
| SCHEMBL481131 | 0.72 | CYP2A6 (0.46) | TRPV4CYP11B2VCAM1ARCYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080135481-A1 | POLYARYLETHERNITRILE HOLLOW FIBER MEMBRANES | GENERAL ELECTRIC COMPANY (US) | 2008-06-12 | — | — | US | claimed |
| WO-2008070216-A1 | POLYARYLETHERNITRILE HOLLOW FIBER MEMBRANES | GENERAL ELECTRIC COMPANY (US) | 2008-06-12 | — | — | WO | claimed |