SCHEMBL101711

SCHEMBL101711

N#Cc1ccc(Cl)cc1Cl

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPV4 Q9HBA0 1/20 0.61
VCAM1 P19320 1/20 0.52
MAOA P21397 2/20 0.48
MAOB P27338 2/20 0.48
TP53 P04637 1/20 0.48
CYP2A6 P11509 1/20 0.47
AR P10275 3/20 0.46
CYP11B2 P19099 2/20 0.46
KDM4E B2RXH2 1/20 0.45
MAPT P10636 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
IDO1 P14902 1/20 0.44
GPR35 Q9HC97 1/20 0.43
GABRA1 P14867 2/20 0.42
GABRG2 P18507 2/20 0.42
GABRB3 P28472 2/20 0.42
GABRB1 P18505 1/20 0.42
GABRB2 P47870 1/20 0.42
TSHR P16473 2/20 0.42
HSD17B10 Q99714 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2198533 0.83 CYP11B2 (0.46) TRPV4VCAM1MAOAMAOBAR
SCHEMBL31441456 0.82 MAOA (0.61) TRPV4VCAM1MAOAMAOBCYP2A6
SCHEMBL7050401 0.82 MAOA (0.61) TRPV4VCAM1MAOAMAOBCYP2A6
SCHEMBL4716620 0.82 TAS1R3 (0.52) TRPV4VCAM1MAOAMAOBAR
SCHEMBL11758987 0.80 AR (0.60) ARMAPTMRGPRX4
SCHEMBL104941 0.80 VCAM1 (0.52) TRPV4VCAM1MAOAMAOBTP53
SCHEMBL27659042 0.78 TRPV4 (0.59) TRPV4MAOAMAOBARCYP11B2
Fluoride SCHEMBL27571082 0.78 VCAM1 (0.50) TRPV4VCAM1MAOAMAOBTP53
SCHEMBL2947436 0.78 TRPV4 (0.59) TRPV4VCAM1ARCYP11B2IDO1
SCHEMBL1566679 0.76 VCAM1 (0.48) TRPV4VCAM1MAOAMAOBCYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 706 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4743438-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF BENZONITRILE COMPOUNDS FROM THE BENZOTRICHLORIDE COMPOUNDS Aarti Industries Limited (IN) 2026-05-20 EP claimed
EP-4665705-A1 A PROCESSES FOR THE PREPARATION OF BENZONITRILE COMPOUNDS FROM THE CORRESPONDING BENZOTRICHLORIDE COMPOUNDS Aarti Industries Limited (IN) 2025-12-24 EP claimed
CN-120192521-A High molecular weight crystallization type polyarylether nitrile and preparation method thereof 电子科技大学 2025-06-24 CN claimed
CN-119977839-A Preparation method of high-purity 2, 4-dichlorobenzonitrile 新泰市华宝化工科技有限公司 2025-05-13 CN claimed
WO-2025068995-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF BENZONITRILE COMPOUNDS FROM THE BENZOTRICHLORIDE COMPOUNDS AARTI INDUSTRIES LIMITED (IN) 2025-04-03 WO claimed
CN-119219522-A Preparation method of 2, 4-difluorobenzonitrile 广西鲲宇药业有限公司 2024-12-31 CN claimed
WO-2024171098-A1 A PROCESSES FOR THE PREPARATION OF BENZONITRILE COMPOUNDS FROM THE CORRESPONDING BENZOTRICHLORIDE COMPOUNDS AARTI INDUSTRIES LIMITED (IN) 2024-08-22 WO claimed
EP-4255947-B1 METHOD FOR THE PRODUCTION OF THERMOPLASTIC POLYOXAZOLIDINONE POLYMERS COVESTRO DEUTSCHLAND AG (DE) 2024-07-03 EP claimed
CN-116351434-B Catalyst for preparing 2, 4-dichlorobenzonitrile, preparation method and application 中南民族大学 2024-05-03 CN claimed
US-20240026065-A1 METHOD FOR THE PRODUCTION OF THERMOPLASTIC POLYOXAZOLIDINONE POLYMERS COVESTRO DEUTSCHLAND AG (DE) 2024-01-25 US claimed
US-5466859-A Process for preparing fluorobenzonitriles HOECHST AKTIENGESELLSCHAFT (DE) 1995-11-14 US claimed
EP-0635486-A2 Process for the preparation of fluorobenzonitriles HOECHST AKTIENGESELLSCHAFT (DE) 1995-01-25 EP claimed
US-5239107-A Reacting a dihalogenobenzonitrile, a dihydric phenol, and an alkali metal salt in the presence of a polymerization solvent IDEMITSU KOSAN CO., LTD. (JP) 1993-08-24 US claimed
US-5187255-A Reacting a dihalogenobenzonitrile, 1,4-bis(4'-halobenzoyl)-benzene and biphenol in aprotic solvent IDEMITSU KOSAN CO., LTD. (JP) 1993-02-16 US claimed
EP-0459332-A2 Process for producing polycyanoaryl ether powder IDEMITSU KOSAN COMPANY LIMITED (JP) 1991-12-04 EP claimed
EP-0429964-A2 Polyether copolymers, a method of producing them, resin compositions containing them, and molded articles formed from them IDEMITSU KOSAN COMPANY LIMITED (JP) 1991-06-05 EP claimed
EP-0186153-B1 PROCESS FOR PREPARING POLYCYANOARYL ETHER POWDER IDEMITSU KOSAN COMPANY LIMITED (JP) 1990-07-25 EP claimed
US-4663427-A Process for preparing polycyanoaryl ether powder IDEMITSU KOSAN COMPANY LIMITED (JP) 1987-05-05 US claimed
EP-0186153-A2 Process for preparing polycyanoaryl ether powder IDEMITSU KOSAN COMPANY LIMITED (JP) 1986-07-02 EP claimed
US-3987016-A METHOD FOR THE PREPARATION OF POLYARYLENE SULFIDES CONTAINING PENDANT CYANO GROUPS BY POLYMERIZING M-BENZENEDITHIOL, DIBROMOBENZENE, AND 2,4-DICHLOROBENZONITRILE THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 1976-10-19 US claimed