Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.52 |
| ▸ | ACHE | P22303 | 5/20 | 0.50 |
| ▸ | BACE1 | P56817 | 4/20 | 0.50 |
| ▸ | BCHE | P06276 | 3/20 | 0.50 |
| ▸ | EZH2 | Q15910 | 2/20 | 0.47 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.47 |
| ▸ | NSD2 | O96028 | 5/20 | 0.46 |
| ▸ | EHMT2 | Q96KQ7 | 3/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.45 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.44 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL3218662 | 0.93 | SIGMAR1 (0.53) | MEN1KMT2APOLBSIGMAR1ACHE | |
| Fumaric Acid SCHEMBL3218644 | 0.93 | SIGMAR1 (0.53) | MEN1KMT2APOLBSIGMAR1ACHE | |
| SCHEMBL4761749 | 0.84 | ALDH1A1 (0.40) | MEN1KMT2APOLB | |
| Acetic Acid SCHEMBL3221646 | 0.81 | ALDH1A1 (0.42) | MEN1KMT2ASIGMAR1 | |
| SCHEMBL4714296 | 0.79 | KDM4E (0.47) | MEN1KMT2APOLBSIGMAR1ACHE | |
| Hydrochloric Acid SCHEMBL3211777 | 0.77 | LMNA (0.42) | MEN1KMT2APOLBSIGMAR1CXCR4 | |
| SCHEMBL3214830 | 0.77 | GRIN2B (0.40) | MEN1KMT2A | |
| SCHEMBL4715098 | 0.76 | HPGD (0.42) | MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL3209458 | 0.75 | HPGD (0.41) | MEN1KMT2A | |
| SCHEMBL4761613 | 0.74 | GRIN2B (0.38) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1917245-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE AS BINDING PARTNERS FOR 5-HT5 RECEPTORS | Abbott GmbH & Co. KG (DE) | 2008-05-07 | — | — | EP | disclosed |
| WO-2007022946-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE AS BINDING PARTNERS FOR 5-HT5 RECEPTORS | ABBOTT GMBH & CO. KG (DE) | 2007-03-01 | — | — | WO | disclosed |