SCHEMBL4718668

SCHEMBL4718668

CC(=O)N1CCCC2CC=CC=C21

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 2/20 0.33
LMNA P02545 1/20 0.32
MTNR1A P48039 1/20 0.30
MTNR1B P49286 1/20 0.30
CYP11B1 P15538 1/20 0.30
CYP11B2 P19099 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3306197 0.86
Hydrochloric Acid SCHEMBL11845673 0.84
SCHEMBL28065144 0.81 ALDH1A1 (0.35)
SCHEMBL11531912 0.81 ALDH1A1 (0.35) LMNA
SCHEMBL11142350 0.79 ALDH1A1 (0.46) LMNA
SCHEMBL23047083 0.75
SCHEMBL4674255 0.75
SCHEMBL29098232 0.74
SCHEMBL28994642 0.74 NOTUM (0.33) NOTUMLMNAMTNR1AMTNR1B
SCHEMBL9238409 0.74 HTR2B (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3174932-B1 CURE ACCELERATORS FOR ANAEROBIC CURABLE COMPOSITIONS Henkel IP & Holding GmbH (DE) 2021-06-09 EP claimed
US-9969863-B2 Cure accelerators for anaerobic curable compositions Henkel IP & Holding GmbH (DE) 2018-05-15 US claimed
US-20170137606-A1 CURE ACCELERATORS FOR ANAEROBIC CURABLE COMPOSITIONS HENKEL AG & CO. KGAA (DE) 2017-05-18 US claimed
CN-114423739-B Improved enantioselective hydrogenation of 4-substituted 1, 2-dihydroquinolines in the presence of chiral iridium catalysts and additives 拜耳公司 2024-06-25 CN disclosed
CN-114514223-B Process for enantioselective hydrogenation of 4-substituted 1, 2-dihydroquinolines comprising using novel iridium catalysts 拜耳公司 2024-05-17 CN disclosed
CN-111902399-B Enantioselective hydrogenation of 4-substituted 1, 2-dihydroquinolines in the presence of chiral iridium catalysts 拜耳公司 2023-11-28 CN disclosed
CN-114514223-A Process comprising enantioselective hydrogenation of 4-substituted 1, 2-dihydroquinolines using a novel iridium catalyst 拜耳公司 2022-05-17 CN disclosed
CN-114423739-A Improved enantioselective hydrogenation of 4-substituted 1, 2-dihydroquinolines in the presence of chiral iridium catalysts and additives 拜耳公司 2022-04-29 CN disclosed
EP-3174932-B1 CURE ACCELERATORS FOR ANAEROBIC CURABLE COMPOSITIONS Henkel IP & Holding GmbH (DE) 2021-06-09 EP disclosed
CN-111902399-A Enantioselective hydrogenation of 4-substituted 1, 2-dihydroquinolines in the presence of chiral iridium catalysts 拜耳公司 2020-11-06 CN disclosed
WO-2018150347-A1 COMPOUNDS WITH BETA-ADRENERGIC AGONIST AND ANTIMUSCARINIC ACTIVITY TORRENT PHARMACEUTICALS LIMITED (IN) 2018-08-23 WO disclosed
WO-2016018553-A1 CURE ACCELERATORS FOR ANAEROBIC CURABLE COMPOSITIONS Henkel IP & Holding GmbH (DE) 2016-02-04 WO disclosed
US-9199915-B2 Process for preparing substituted biphenyls by C-H activation BAYER CROPSCIENCE AG (DE) 2015-12-01 US disclosed
US-20150203440-A1 PROCESS FOR PREPARING SUBSTITUTED BIPHENYLS BY C-H ACTIVATION BAYER CROPSCIENCE AG (DE) 2015-07-23 US disclosed
EP-2880013-A1 PROCESS FOR PREPARING SUBSTITUTED BIPHENYLS BY C-H ACTIVATION Bayer CropScience AG (DE) 2015-06-10 EP disclosed
WO-2014019995-A1 PROCESS FOR PREPARING SUBSTITUTED BIPHENYLS BY C-H ACTIVATION BAYER CROPSCIENCE AG (DE) 2014-02-06 WO disclosed
EP-1940819-A1 PHOSPHODIESTERASE 10 INHIBITORS Memory Pharmaceuticals Corporation (US) 2008-07-09 EP disclosed
US-20070093515-A1 Phosphodiesterase 10 inhibitors AMGEN INC. 2007-04-26 US disclosed
WO-2007022280-A1 PHOSPHODIESTERASE 10 INHIBITORS MEMORY PHARMACEUTICALS CORPORATION (US) 2007-02-22 WO disclosed
US-20060160814-A1 Phosphodiesterase 10 inhibitors MEMORY PHARMACEUTICALS CORPORATION 2006-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070093515-A1 Phosphodiesterase 10 inhibitors PDE7A, PDE12, PDE10A NOTUM 406/4885LMNA 4307/4885MTNR1A 2702/4885
US-20170137606-A1 CURE ACCELERATORS FOR ANAEROBIC CURABLE COMPOSITIONS AHCY, AHCYL1, MGMT NOTUM 2204/4885LMNA 3159/4885MTNR1A 3236/4885
US-20060160814-A1 Phosphodiesterase 10 inhibitors PDE5A, PDE3A, PDE2A NOTUM 535/4885LMNA 1512/4885MTNR1A 1410/4885
US-20150203440-A1 PROCESS FOR PREPARING SUBSTITUTED BIPHENYLS BY C-H ACTIVATION CYP1A1, CBR1, AHR NOTUM 2166/4885LMNA 3277/4885MTNR1A 334/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.