Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 13/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4720166 | 0.79 | GPR119 (0.33) | GPR119 | |
| SCHEMBL4594886 | 0.78 | GNAI3 (0.38) | GPR119 | |
| SCHEMBL4654454 | 0.77 | ITGB3 (0.40) | GPR119EPHX1EPHX2 | |
| SCHEMBL212033 | 0.75 | CHRM2 (0.42) | GPR119HRH3EPHX1HPGD | |
| SCHEMBL1935995 | 0.73 | CHRM2 (0.34) | GPR119HRH3EPHX1HPGD | |
| SCHEMBL4064598 | 0.72 | USP2 (0.33) | GPR119EPHX1HPGD | |
| SCHEMBL2326335 | 0.71 | EPHX1 (0.40) | EPHX1HPGD | |
| SCHEMBL1133757 | 0.71 | NR1H2 (0.43) | GPR119EPHX1EPHX2HPGD | |
| SCHEMBL373788 | 0.71 | SMN1; SMN2 (0.43) | HRH3HPGD | |
| SCHEMBL29191941 | 0.71 | CTSK (0.52) | EPHX1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1558600-B1 | SELECTED CGRP ANTAGONISTS, METHOD FOR PRODUCTION AND USE THEREOF AS MEDICAMENT | BOEHRINGER INGELHEIM PHARMA (DE) | 2008-05-07 | — | — | EP | disclosed |