Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 13/20 | 0.33 |
| ▸ | HPGDS | O60760 | 3/20 | 0.32 |
| ▸ | LIPE | Q05469 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4719233 | 0.79 | GPR119 (0.39) | GPR119 | |
| SCHEMBL4718432 | 0.77 | ALDH1A1 (0.34) | GPR119 | |
| SCHEMBL4594886 | 0.77 | GNAI3 (0.38) | GPR119 | |
| SCHEMBL5165695 | 0.76 | LMNA (0.38) | GPR119 | |
| SCHEMBL28058828 | 0.74 | OPRM1 (0.35) | OPRM1OPRD1OPRK1 | |
| SCHEMBL212033 | 0.74 | CHRM2 (0.42) | GPR119 | |
| SCHEMBL1133757 | 0.73 | NR1H2 (0.43) | GPR119 | |
| SCHEMBL4654454 | 0.73 | ITGB3 (0.40) | GPR119 | |
| SCHEMBL1935995 | 0.72 | CHRM2 (0.34) | GPR119 | |
| SCHEMBL5258386 | 0.72 | NCF1 (0.40) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1558600-B1 | SELECTED CGRP ANTAGONISTS, METHOD FOR PRODUCTION AND USE THEREOF AS MEDICAMENT | BOEHRINGER INGELHEIM PHARMA (DE) | 2008-05-07 | — | — | EP | disclosed |