Biphenyl

Biphenyl

SCHEMBL472033

O=C(O)CO.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.58
PTGS1 P23219 2/20 0.58
GAA P10253 2/20 0.58
ABCC4 O15439 1/20 0.58
TSHR P16473 1/20 0.58
HTT P42858 1/20 0.58
FFAR1 O14842 2/20 0.54
ALDH1A1 P00352 1/20 0.53
SMN1; SMN2 Q16637 4/20 0.52
CYP1A2 P05177 1/20 0.52
RAB9A P51151 1/20 0.52
HIF1A Q16665 1/20 0.52
MMP2 P08253 1/20 0.50
MMP7 P09237 1/20 0.50
MMP14 P50281 1/20 0.50
MAPT P10636 2/20 0.48
L3MBTL1 Q9Y468 2/20 0.48
PTPN1 P18031 1/20 0.48
GSK3B P49841 1/20 0.48
AKR1B1 P15121 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tannin Pyrogallol SCHEMBL27894654 0.97 LMNA (0.62) LMNAPTGS1GAAABCC4TSHR
Glycolic Acid SCHEMBL9756751 0.88 LMNA (0.50) LMNAPTGS1GAAABCC4TSHR
Biphenyl SCHEMBL23270852 0.87 ALDH1A1 (0.69) LMNAPTGS1GAAABCC4TSHR
Biphenyl SCHEMBL27350250 0.83 BCAT2 (0.52) LMNAPTGS1GAAABCC4TSHR
Glycolic Acid SCHEMBL8854226 0.83 KMO (0.52) LMNAPTGS1GAAABCC4TSHR
Naphthalene SCHEMBL28240036 0.82 PTPN7 (0.48) GAAFFAR1ALDH1A1SMN1; SMN2CYP1A2
Biphenyl SCHEMBL6525433 0.82 LMNA (0.58) LMNAPTGS1GAAABCC4TSHR
Biphenyl SCHEMBL4132218 0.82 FFAR1 (0.71) LMNAPTGS1GAAABCC4TSHR
Biphenyl SCHEMBL1029706 0.82 LMNA (0.58) LMNAPTGS1GAAABCC4TSHR
Biphenyl SCHEMBL5573670 0.81 ALDH1A1 (0.60) LMNAPTGS1GAAABCC4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 346 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111511809-B Curing agent composition and resin composition containing the same 赫克塞尔合成有限公司 2024-08-16 CN claimed
CN-110740725-B Composition containing benzoic acid amide compound and cyclodextrin solubilizer 株式会社爱茉莉太平洋 2024-01-12 CN claimed
CN-108586229-A The synthesis of diphenyl hydroxyacetic acid 烟台智本知识产权运营管理有限公司 2018-09-28 CN claimed
CN-104725727-A Polypropylene composite containing microalgae and preparing method thereof WUXI TAIHU LAKE BLUE ALGAE RESOURCES APPLIC TECHNOLOGY RES INST CO LTD 2015-06-24 CN claimed
US-8557730-B2 Composition and process for making the composition MOLYCORP MINERALS, LLC (US) 2013-10-15 US claimed
US-8252087-B2 Process and apparatus for treating a gas containing a contaminant MOLYCORP MINERALS, LLC (US) 2012-08-28 US claimed
US-8114775-B2 Dihydroxy enol compounds used in chemical mechanical polishing compositions having metal ion oxidizers DUPONT AIR PRODUCTS NANOMATERIALS, LLC (US) 2012-02-14 US claimed
CN-101225235-B Preparation method of highly-hydrophobic biodegradable soy protein plastic and uses thereof UNIV WUHAN 2011-05-18 CN claimed
US-20100168498-A1 APPARATUS AND PROCESS FOR TREATING AN AQUEOUS SOLUTION CONTAINING CHEMICAL CONTAMINANTS MOLYCORP MINERALS, LLC (US) 2010-07-01 US claimed
EP-1871855-B1 DIHYDROXY ENOL COMPOUNDS USED IN CHEMICAL MECHANICAL POLISHING COMPOSITIONS HAVING METAL ION OXIDIZERS DUPONT AIR PROD NANOMATERIALS (US) 2010-03-24 EP claimed
US-5621006-A TOPICALLY APPLYING IN A VEHICLE, E.G. HYDROXYACIDS, KETOACIDS AND SALTS, ESTERS THEREOF YU RUEY J (US) 1997-04-15 US claimed
EP-0599819-B1 Use of hydroxycarboxylic acids and derivatives for the preparation of topical dermatologic compositions for the treatment of wrinkles SCOTT EUGENE J VAN (US) 1997-04-02 EP claimed
US-5561158-A Compositions comprising 2-hydroxycarboxylic acids and related compounds, and methods for alleviating signs of dermatological aging TRISTRATA, INCORPORATED 1996-10-01 US claimed
US-5561157-A INCLUDES ORGANIC ALPHA AND BETA HYDROXY OR KETO CARBOXYLIC ACIDS, ESTERS, LACTONES AND/OR SALTS; USED FOR SKIN DISORDERS TRISTRATA INC (US) 1996-10-01 US claimed
US-5554654-A COMPRISING SALICYLIC ACID, RETINOIC ACID, ERYTHROMYCIN, METRONIDAZOLE, TETRACYCLINE, CLINDAMYCIN, MINOCYCLINE, MECLOCYCLINE OR BENZILIC ACID BY COMBINING WITH 2-HYDROXY ACID, 2-KETOACID, DERIVATIVE THEREOF OR RELATED COMPOUND TRISTRATA INC (US) 1996-09-10 US claimed
US-5554597-A Compositions comprising 2-hydroxycarboxylic acids and related compounds, and methods for alleviating signs of dermatological aging TRISTRATA INC (US) 1996-09-10 US claimed
US-5554652-A TOPICALLY APPLYING MIXTURE TO REDUCE OR PREVENT SKIN DISORDERS TRISTRATA INC (US) 1996-09-10 US claimed
EP-0273202-B1 Use of hydroxycarboxylic acids to enhance therapeutic effects of topical compositions for fungal infections and pigmented spots. SCOTT EUGENE J VAN (US) 1995-06-21 EP claimed
EP-0599819-A2 Additives enhancing topical actions of therapeutic agents Van Scott, Eugene J., Dr. (US) 1994-06-01 EP claimed
EP-0273202-A2 Use of hydroxycarboxylic acids to enhance therapeutic effects of topical compositions for fungal infections and pigmented spots. Van Scott, Eugene J., Dr. (US) 1988-07-06 EP claimed