Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.32 |
| ▸ | AKR1B10 | O60218 | 4/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
| ▸ | PRKX | P51817 | 1/20 | 0.31 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.30 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.30 |
| ▸ | XPO1 | O14980 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | TTR | P02766 | 1/20 | 0.30 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14102047 | 0.91 | AR (0.34) | ARCXCR3RETPRKXTAOK1 | |
| SCHEMBL4720926 | 0.89 | WDR5 (0.33) | ARCXCR3AKR1B10RETPRKX | |
| SCHEMBL4724885 | 0.81 | SMPD3 (0.37) | — | |
| SCHEMBL4724899 | 0.81 | SMPD3 (0.37) | — | |
| SCHEMBL4724015 | 0.81 | MAPT (0.34) | ARP2RX7NTRK1LMNANPSR1 | |
| SCHEMBL4722057 | 0.81 | GRIN2B (0.35) | AKR1B10P2RX7AKR1B1 | |
| SCHEMBL4723684 | 0.79 | WDR5 (0.34) | ARRETPRKXTAOK1 | |
| SCHEMBL14101709 | 0.78 | F10 (0.39) | CXCR3AKR1B10 | |
| SCHEMBL4720017 | 0.78 | CXCR3 (0.31) | CXCR3 | |
| SCHEMBL4721386 | 0.78 | SMN1; SMN2 (0.33) | RETPRKXTAOK1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |