Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | PRKX | P51817 | 1/20 | 0.33 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | ALPI | P09923 | 1/20 | 0.33 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.32 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4723684 | 0.90 | WDR5 (0.34) | WDR5RETPRKXTAOK1AR | |
| SCHEMBL4722667 | 0.89 | AR (0.34) | RETPRKXTAOK1ARAKR1B1 | |
| SCHEMBL14101709 | 0.89 | F10 (0.39) | ALPLALPIAKR1B10AKR1C4AKR1C3 | |
| SCHEMBL4721921 | 0.86 | CXCR3 (0.33) | WDR5ALPLALPICXCR3MAPT | |
| SCHEMBL4720618 | 0.85 | F10 (0.36) | CXCR3F10 | |
| SCHEMBL4720620 | 0.85 | F10 (0.36) | CXCR3F10 | |
| SCHEMBL4718815 | 0.85 | TSHR (0.37) | RETPRKXTAOK1AKR1B10AKR1C4 | |
| SCHEMBL14102047 | 0.84 | AR (0.34) | RETPRKXTAOK1ARKMT2A | |
| SCHEMBL14101712 | 0.83 | F10 (0.39) | ALPLALPICXCR3MAPTSLC16A3 | |
| SCHEMBL4722372 | 0.82 | F10 (0.38) | ALPLALPICXCR3MAPTSLC16A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |