SCHEMBL472323

SCHEMBL472323

C=Cc1ccc2cc(C(=O)Cl)ccc2c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.44
ALDH1A1 P00352 2/20 0.44
KDM4E B2RXH2 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
MEN1 O00255 1/20 0.44
EGFR P00533 1/20 0.44
TP53 P04637 1/20 0.44
MAPT P10636 1/20 0.44
PKM P14618 1/20 0.44
HPGD P15428 1/20 0.44
ALOX15 P16050 1/20 0.44
ALOX12 P18054 1/20 0.44
JAK1 P23458 1/20 0.44
MAPK1 P28482 1/20 0.44
KMT2A Q03164 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
HSD17B10 Q99714 1/20 0.44
PLAU P00749 2/20 0.39
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11963928 0.83 KDM4E (0.50) CYP3A4ALDH1A1KDM4ETDP1MEN1
SCHEMBL31413604 0.83 KDM4E (0.50) CYP3A4ALDH1A1KDM4ETDP1MEN1
SCHEMBL727139 0.82 CES2 (0.52) CYP3A4ALDH1A1KDM4ETDP1MEN1
SCHEMBL29375279 0.82 CES2 (0.52) CYP3A4ALDH1A1KDM4ETDP1MEN1
Hydrochloric Acid SCHEMBL472326 0.81 KDM4E (0.49) CYP3A4ALDH1A1KDM4ETDP1MEN1
SCHEMBL10077147 0.81 CYP3A4 (0.44) CYP3A4ALDH1A1KDM4ETDP1MEN1
SCHEMBL362842 0.80 ALDH1A1 (0.52) ALDH1A1TDP1KMT2ATAS1R3TAS1R1
Acetic Acid SCHEMBL11898840 0.79 KDM4E (0.50) CYP3A4ALDH1A1KDM4ETDP1MEN1
SCHEMBL8775402 0.78 LCK (0.48) CYP3A4ALDH1A1KDM4ETDP1MEN1
SCHEMBL4590567 0.77 PTPN11 (0.53) ALDH1A1KDM4ETDP1MEN1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105607426-B Polymer, chemical amplification negative resist composition and pattern forming method SHIN ETSU CHEMICAL COMPANY (JP) 2019-11-01 CN disclosed
CN-102516453-B Polymer, chemically amplified negative resist composition and pattern forming method SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-06-01 CN disclosed
CN-105607426-A Polymer, chemically amplified negative resist composition, and patterning process SHINETSU CHEMICAL CO 2016-05-25 CN disclosed
EP-2412733-B1 Polymer, chemically amplified negative resist composition, and patterning process SHINETSU CHEMICAL CO (JP) 2016-03-23 EP disclosed
EP-2412733-B1 Polymer, chemically amplified negative resist composition, and patterning process SHINETSU CHEMICAL CO (JP) 2016-03-23 EP disclosed
US-8470512-B2 Polymer, chemically amplified negative resist composition, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2013-06-25 US disclosed
US-8470512-B2 Polymer, chemically amplified negative resist composition, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2013-06-25 US disclosed
US-8470512-B2 Polymer, chemically amplified negative resist composition, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2013-06-25 US disclosed
CN-102516453-A Polymer, chemically amplified negative resist composition and pattern forming method SHINETSU CHEMICAL CO 2012-06-27 CN disclosed
US-20120028190-A1 POLYMER, CHEMICALLY AMPLIFIED NEGATIVE RESIST COMPOSITION, AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-02-02 US disclosed
US-20120028190-A1 POLYMER, CHEMICALLY AMPLIFIED NEGATIVE RESIST COMPOSITION, AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-02-02 US disclosed
EP-2412733-A1 Polymer, chemically amplified negative resist composition, and patterning process Shin-Etsu Chemical Co., Ltd. (JP) 2012-02-01 EP disclosed
EP-2412733-A1 Polymer, chemically amplified negative resist composition, and patterning process Shin-Etsu Chemical Co., Ltd. (JP) 2012-02-01 EP disclosed