Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 13/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | WNT3A | P56704 | 3/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4724962 | 0.92 | JAK3 (0.33) | JAK3 | |
| SCHEMBL4721381 | 0.90 | IMPDH2 (0.34) | JAK3 | |
| SCHEMBL4720488 | 0.87 | P2RX7 (0.34) | JAK3 | |
| SCHEMBL4720492 | 0.87 | P2RX7 (0.34) | JAK3 | |
| SCHEMBL4719688 | 0.87 | GHSR (0.31) | — | |
| SCHEMBL4721936 | 0.86 | SYK (0.31) | — | |
| SCHEMBL4723056 | 0.85 | LMNA (0.32) | — | |
| SCHEMBL4724965 | 0.85 | FFAR1 (0.33) | — | |
| SCHEMBL4720665 | 0.84 | PTK2 (0.31) | JAK3 | |
| SCHEMBL4720659 | 0.84 | PTK2 (0.31) | JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |