Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7279889 | 0.90 | MMP12 (0.68) | MMP12ALDH1A1TSHRKMT2ASMN1; SMN2 | |
| SCHEMBL11394897 | 0.84 | MMP12 (0.69) | MMP12ALDH1A1TSHRKMT2ASMN1; SMN2 | |
| SCHEMBL462586 | 0.81 | MMP12 (0.58) | MMP12ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL2939724 | 0.78 | MMP12 (0.54) | MMP12ALDH1A1TSHRKMT2ASMN1; SMN2 | |
| SCHEMBL1532473 | 0.78 | MMP12 (0.54) | MMP12ALDH1A1TSHRKMT2ASMN1; SMN2 | |
| SCHEMBL7344014 | 0.77 | PPARG (0.55) | MMP12ALDH1A1TSHR | |
| SCHEMBL7344016 | 0.77 | PPARG (0.55) | MMP12ALDH1A1TSHR | |
| SCHEMBL17008814 | 0.77 | MMP12 (0.52) | MMP12ALDH1A1TSHRKMT2ASMN1; SMN2 | |
| SCHEMBL29257741 | 0.77 | MMP12 (0.52) | MMP12ALDH1A1TSHRKMT2ASMN1; SMN2 | |
| SCHEMBL5694346 | 0.76 | MMP12 (1.00) | MMP12TSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008013949-A2 | MOLECULAR DESIGN OF THERMOSTABLE ALCOHOL DEHYDROGENASE FOR SYNTHESIS FOR CHIRAL AROMATIC ALCOHOLS | MICHIGAN STATE UNIVERSITY (US) | 2008-01-31 | — | — | WO | disclosed |