Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7279889 | 0.91 | MMP12 (0.68) | MMP12ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL27556300 | 0.81 | ALDH1A1 (0.51) | ALDH1A1TDP1TSHRSMN1; SMN2 | |
| SCHEMBL6559718 | 0.81 | ALDH1A1 (0.51) | ALDH1A1TDP1TSHRSMN1; SMN2 | |
| SCHEMBL11394897 | 0.81 | MMP12 (0.69) | MMP12ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL4725100 | 0.81 | MMP12 (0.61) | MMP12ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL14764231 | 0.81 | ALDH1A1 (0.47) | MMP12ALDH1A1TDP1TSHRSMN1; SMN2 | |
| SCHEMBL4351183 | 0.78 | ALDH1A1 (0.64) | MMP12ALDH1A1TDP1TSHRSMN1; SMN2 | |
| SCHEMBL111422 | 0.78 | ALDH1A1 (0.64) | MMP12ALDH1A1TDP1TSHRSMN1; SMN2 | |
| Benzene SCHEMBL19304565 | 0.78 | ALDH1A1 (0.64) | MMP12ALDH1A1TDP1TSHRSMN1; SMN2 | |
| SCHEMBL13825187 | 0.78 | ALOX15 (0.44) | ALDH1A1TDP1TSHRSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2404891-B1 | PREPARATION METHOD OF ACYLBENZENES | DSM IP ASSETS BV (NL) | 2015-09-02 | — | — | EP | disclosed |
| US-8642800-B2 | Preparation method of acylbenzenes | DSM IP ASSETS B.V. (NL) | 2014-02-04 | — | — | US | disclosed |
| US-20120022284-A1 | PREPARATION METHOD OF ACYLBENZENES | DSM IP ASSETS B.V. (NL) | 2012-01-26 | — | — | US | disclosed |
| EP-2404891-A1 | PREPARATION METHOD OF ACYLBENZENES | DSM IP Assets B.V. (NL) | 2012-01-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022284-A1 | PREPARATION METHOD OF ACYLBENZENES | ACACB, SDHB, TET2 | MMP12 2525/4885ALDH1A1 1535/4885TDP1 4854/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.