Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | DAGLB | Q8NCG7 | 1/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GHSR | Q92847 | 1/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4725329 | 0.86 | OPRD1 (0.50) | OPRD1DAGLBMKNK1MKNK2PTGES | |
| SCHEMBL4725337 | 0.86 | OPRD1 (0.50) | OPRD1DAGLBMKNK1MKNK2PTGES | |
| SCHEMBL8222689 | 0.82 | CHRNB4 (0.48) | KDM4EGHSRALDH1A1TDP1CHRNA7 | |
| SCHEMBL4781860 | 0.80 | DAGLB (0.46) | DAGLBMKNK1MKNK2PTGESKDM4E | |
| SCHEMBL4781855 | 0.80 | DAGLB (0.46) | DAGLBMKNK1MKNK2PTGESKDM4E | |
| SCHEMBL4781779 | 0.79 | KIF11 (0.34) | OPRD1PTGESKDM4EPOLBALDH1A1 | |
| SCHEMBL8224323 | 0.74 | GPR119 (0.51) | DAGLBPTGESKDM4EGHSRMEN1 | |
| SCHEMBL4781848 | 0.73 | OPRD1 (0.53) | OPRD1DAGLBPTGESGHSRCYP17A1 | |
| SCHEMBL4794880 | 0.73 | OPRD1 (0.53) | OPRD1DAGLBPTGESGHSRCYP17A1 | |
| SCHEMBL4834222 | 0.72 | CYP1A2 (0.40) | OPRD1KDM4EPOLBMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008018639-A2 | GLYCINE TRANSPORTER INHIBITOR | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2008-02-14 | — | — | WO | disclosed |