Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.40 |
| ▸ | FASN | P49327 | 1/20 | 0.40 |
| ▸ | DAGLA | Q9Y4D2 | 5/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ABHD6 | Q9BV23 | 3/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3076592 | 0.91 | LMNA (0.44) | TSHR | |
| SCHEMBL3076594 | 0.91 | LMNA (0.44) | TSHR | |
| SCHEMBL3533488 | 0.90 | TSHR (0.45) | TSHR | |
| SCHEMBL4777579 | 0.88 | HSD17B2 (0.43) | HSD17B2 | |
| SCHEMBL4781855 | 0.88 | DAGLB (0.46) | CYP17A1MEN1KMT2A | |
| SCHEMBL4781860 | 0.88 | DAGLB (0.46) | CYP17A1MEN1KMT2A | |
| SCHEMBL5177302 | 0.87 | DPP4 (0.46) | TSHRSMN1; SMN2 | |
| SCHEMBL3540440 | 0.87 | DPP4 (0.46) | TSHRSMN1; SMN2 | |
| SCHEMBL4781869 | 0.83 | USP30 (0.43) | HSD17B2 | |
| SCHEMBL28381807 | 0.81 | CYP2D6 (0.41) | MAPK1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008018639-A2 | GLYCINE TRANSPORTER INHIBITOR | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2008-02-14 | — | — | WO | disclosed |