Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 3/20 | 0.43 |
| ▸ | FABP4 | P15090 | 1/20 | 0.42 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4776197 | 0.92 | ROCK2 (0.42) | HSD17B2FABP4 | |
| SCHEMBL4776201 | 0.92 | ROCK2 (0.42) | HSD17B2FABP4 | |
| SCHEMBL4725342 | 0.88 | HPGD (0.41) | HSD17B2 | |
| SCHEMBL3076594 | 0.88 | LMNA (0.44) | LMNAKDM4E | |
| SCHEMBL3076592 | 0.88 | LMNA (0.44) | LMNAKDM4E | |
| SCHEMBL4726621 | 0.86 | DAGLB (0.42) | FABP4 | |
| SCHEMBL4726619 | 0.86 | DAGLB (0.42) | FABP4 | |
| SCHEMBL3533488 | 0.86 | TSHR (0.45) | LMNAKDM4E | |
| SCHEMBL3517661 | 0.85 | L3MBTL3 (0.41) | FABP4SLC6A9 | |
| SCHEMBL3517602 | 0.85 | L3MBTL3 (0.41) | FABP4SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008018639-A2 | GLYCINE TRANSPORTER INHIBITOR | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2008-02-14 | — | — | WO | disclosed |