Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.34 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 4/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4779771 | 0.83 | NOTUM (0.51) | NOTUMCHRM3SMN1; SMN2CHRM2CHRM4 | |
| SCHEMBL4725344 | 0.81 | NOTUM (0.36) | HRH1NOTUMACSS2CHRM3SMN1; SMN2 | |
| SCHEMBL4725202 | 0.81 | SMN1; SMN2 (0.42) | ACSS2CHRM3TAAR1HTR2ASMN1; SMN2 | |
| SCHEMBL14291874 | 0.78 | CYP2D6 (0.45) | NOTUMCHRM3HTR2ASMN1; SMN2CHRM2 | |
| SCHEMBL4777782 | 0.78 | MEN1 (0.35) | NOTUMACSS2CHRM3CHRM2CHRM4 | |
| SCHEMBL11826155 | 0.72 | RORC (0.42) | ACSS2CHRM3SMN1; SMN2CHRM2CHRM4 | |
| SCHEMBL8354939 | 0.72 | CYP4F2 (0.48) | ACSS2MEN1KMT2A | |
| SCHEMBL4725530 | 0.72 | CHRM3 (0.41) | HRH1ACSS2CHRM3HTR2ASMN1; SMN2 | |
| Bromide SCHEMBL4727947 | 0.71 | LMNA (0.42) | HRH1ACSS2CHRM3HTR2ASMN1; SMN2 | |
| SCHEMBL11804748 | 0.69 | NOTUM (0.64) | NOTUMSMN1; SMN2MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008023157-A1 | NITROGEN CONTAINING HETEROCYCLIC COMPOUNDS USEFUL AS M3-RECEPTOR MODULATORS | ARGENTA DISCOVERY LIMITED (GB) | 2008-02-28 | — | — | WO | disclosed |
| WO-2008023157-A1 | NITROGEN CONTAINING HETEROCYCLIC COMPOUNDS USEFUL AS M3-RECEPTOR MODULATORS | ARGENTA DISCOVERY LIMITED (GB) | 2008-02-28 | — | — | WO | disclosed |